Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	107526
Country	China

Received	2025-04-08 11:02
Peer-Review Started	2025-04-08 11:02
To Make the First Decision
Return for Revision	2025-04-17 10:37
Revised	2025-05-08 00:53
Second Decision	2025-07-08 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-08 06:21
Articles in Press	2025-07-08 06:21
Publication Fee Transferred	2025-05-16 09:16
Edit the Manuscript by Language Editor	2025-07-13 18:40
Typeset the Manuscript	2025-08-01 02:07
Publish the Manuscript Online	2025-08-14 05:49

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Intraoperative laparoscopic ultrasound-guided resection and microwave ablation for colorectal liver metastases
Manuscript Source	Unsolicited Manuscript
All Author List	Hao-Ran Wu, Hao Bu, You-Yuan Liu, Hou-Ping Zhou, Jing-Song Ye and Hua Chen
ORCID	Author(s) ORCID Number Hua Chen http://orcid.org/0009-0000-3853-3396
Funding Agency and Grant Number	Funding Agency Grant Number National Clinical Key Specialty Major Research Project of Hunan Provincial Health Commission in 2023 No. Z2023165
Corresponding Author	Hua Chen, Professor, Department of General Surgery, Changde Hospital, Xiangya School of Medicine, Central South University, No. 818 Renmin Road, Wuling District, Changde 415000, Hunan Province, China. monday202003@163.com
Key Words	Laparoscopy; Ultrasound guidance; Surgical resection; Microwave ablation; Colon cancer; Liver metastases
Core Tip	This study demonstrates that intraoperative laparoscopic ultrasound [contrast-enhanced ultrasound with Sonazoid (S-CEUS)]-guided surgical resection and microwave ablation significantly enhances clinical outcomes in colorectal cancer liver metastasis patients compared to preoperative ethoxybenzyl diethylenetriamine penta-acetic acid enhanced magnetic resonance imaging planning. The S-CEUS group exhibited superior oncologic efficacy (higher 5-year survival: 32% vs 18%), fewer adverse events, and improved quality of life (Karnofsky Performance Status scores). Multivariate analysis confirmed intraoperative S-CEUS utilization and primary tumor differentiation as independent prognostic factors. These findings highlight S-CEUS-guided strategies as a critical advancement for optimizing oncologic precision and long-term survival in metastatic liver surgery, warranting broader clinical adoption.
Publish Date	2025-08-14 05:49
Citation	<p>Wu HR, Bu H, Liu YY, Zhou HP, Ye JS, Chen H. Intraoperative laparoscopic ultrasound-guided resection and microwave ablation for colorectal liver metastases. <i>World J Gastrointest Oncol</i> 2025; 17(8): 107526</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i8/107526.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i8.107526

Full Article (PDF)	WJGO-17-107526-with-cover.pdf
Manuscript File	107526_Auto_Edited_070011.docx
Answering Reviewers	107526-answering-reviewers.pdf
Audio Core Tip	107526-audio.mp3
Biostatistics Review Certificate	107526-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	107526-conflict-of-interest-statement.pdf
Copyright License Agreement	107526-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	107526-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	107526-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	107526-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	107526-non-native-speakers.pdf
Peer-review Report	107526-peer-reviews.pdf
Scientific Misconduct Check	107526-scientific-misconduct-check.png
Scientific Editor Work List	107526-scientific-editor-work-list.pdf
CrossCheck Report	107526-crosscheck-report.pdf