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Articles Published Processes
7/14/2025 12:55:52 PM | Browse: 5 | Download: 27
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Received |
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2025-03-27 05:04 |
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Peer-Review Started |
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2025-03-27 05:04 |
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To Make the First Decision |
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Return for Revision |
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2025-04-02 07:41 |
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2025-04-12 03:23 |
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Second Decision |
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2025-05-27 02:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-27 07:20 |
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Articles in Press |
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2025-05-27 07:20 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-29 12:23 |
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Publish the Manuscript Online |
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2025-07-14 12:55 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Exploring the role of neutrophil extracellular traps in colorectal cancer: Insights from single-cell sequencing
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zhen-Xi Xu, Fan-Yong Qu, Zheng Zhang, Wen-Yu Luan, Si-Xiang Lin and Yan-Dong Miao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shandong Province Medical and Health Science and Technology Development Plan Project |
No. 202203030713 |
| Yantai Science and Technology Program |
No. 2024YD005 |
| Yantai Science and Technology Program |
No. 2024YD007 |
| Yantai Science and Technology Program |
No. 2024YD010 |
| Science and Technology Program of Yantai Affiliated Hospital of Binzhou Medical University |
No. YTFY2022KYQD06 |
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| Corresponding Author |
Yan-Dong Miao, Cancer Center, Yantai Affiliated Hospital of Binzhou Medical University, The Second Medical College of Binzhou Medical University, No. 717 Jinbu Street, Muping District, Yantai 264100, Shandong Province, China. miaoyd_22@bzmc.edu.cn |
| Key Words |
Neutrophil extracellular traps; Colorectal cancer; Single-cell sequencing; Tumor microenvironment; Therapeutic targets |
| Core Tip |
Neutrophil extracellular traps (NETs) play a critical role in the progression of colorectal cancer (CRC), impacting tumor metastasis, immune evasion, and angiogenesis. Recent advancements in single-cell sequencing (SCS) have provided deeper insights into the mechanisms behind NET formation and their interactions within the tumor microenvironment. SCS has revealed that NETs not only facilitate CRC cell invasion and metastasis but also promote an immunosuppressive environment by inhibiting T cell activity. This makes NETs a promising therapeutic target for CRC, potentially enhancing early diagnosis, treatment efficacy, and patient prognosis by targeting key regulatory pathways of NET formation. |
| Publish Date |
2025-07-14 12:55 |
| Citation |
<p>Xu ZX, Qu FY, Zhang Z, Luan WY, Lin SX, Miao YD. Exploring the role of neutrophil extracellular traps in colorectal cancer: Insights from single-cell sequencing. <i>World J Gastrointest Oncol</i> 2025; 17(7): 107589</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i7/107589.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i7.107589 |
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