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Articles Published Processes
9/25/2025 3:33:09 AM | Browse: 83 | Download: 23
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Received |
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2025-03-30 11:31 |
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Peer-Review Started |
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2025-03-30 11:31 |
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To Make the First Decision |
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Return for Revision |
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2025-05-12 19:31 |
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Revised |
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2025-06-18 18:27 |
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Second Decision |
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2025-08-22 02:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-22 07:09 |
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Articles in Press |
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2025-08-22 07:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-08-30 06:24 |
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Typeset the Manuscript |
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2025-09-22 02:07 |
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Publish the Manuscript Online |
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2025-09-25 03:33 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Considerations and clinical utility of referral pathways for early detection of liver disease in at-risk populations
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jesse Pustjens, Willem P Brouwer, Ibrahim Ayada, Harry L A Janssen and Laurens A van Kleef |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Laurens A van Kleef, MD, PhD, Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Room Na-606, Postbus 2040, Rotterdam 3000, Zuid-Holland, Netherlands. l.vankleef@erasmusmc.nl |
| Key Words |
Screening; Fibrosis; Advanced liver disease; General population; Epidemiology |
| Core Tip |
Early detection of liver fibrosis in community settings is essential to timely intervene and prevent liver related events. Although non-invasive testing strategies are likely to be cost-effective, their uptake by non-hepatology specialists is limited. Key challenges include the use of overly broad target populations and suboptimal selection or application of non-invasive tests (NITs). Optimizing these pathways by integrating better NITs and refining referral algorithms can improve risk stratification, minimize unnecessary specialist referrals, reduce the burden on healthcare systems, and facilitate timely, multidisciplinary care for individuals at highest risk of liver related adverse outcomes. |
| Publish Date |
2025-09-25 03:33 |
| Citation |
<p>Pustjens J, Brouwer WP, Ayada I, Janssen HLA, van Kleef LA. Considerations and clinical utility of referral pathways for early detection of liver disease in at-risk populations. <i>World J Gastroenterol</i> 2025; 31(37): 107665</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i37/107665.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i37.107665 |
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