BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
7/24/2025 9:11:32 AM | Browse: 154 | Download: 485
 |
Received |
|
2025-03-28 04:13 |
|
Peer-Review Started |
|
2025-03-28 04:13 |
|
First Decision by Editorial Office Director |
|
2025-04-09 12:28 |
|
Return for Revision |
|
2025-04-09 12:28 |
|
Revised |
|
2025-04-22 14:59 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2025-06-11 02:44 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-06-13 06:51 |
|
Articles in Press |
|
2025-06-13 06:51 |
|
Edit the Manuscript by Language Editor |
|
2025-06-18 19:03 |
|
Typeset the Manuscript |
|
2025-07-17 06:47 |
|
Publish the Manuscript Online |
|
2025-07-24 09:11 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Regulation and intervention of stem cell differentiation by long non-coding RNAs: Mechanisms and therapeutic potential
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ye-Hua Li, Yi-Ning Yao, Shen-Ao Zhou and Yang Wang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
32200755, 32200621 |
| Natural Science Foundation of Gansu Province |
23JRRA696 |
|
| Corresponding Author |
Yang Wang, PhD, School of Life Sciences, Fudan University, No. 2005 Songhu Road, Yangpu District, Shanghai 200438, China. w_yang@fudan.edu.cn |
| Key Words |
Long non-coding RNAs; Stem cell differentiation; MicroRNA sponges; Epigenetic regulation; Regenerative medicine; Delivery and precise targeting; Stem cell therapy |
| Core Tip |
As key regulators of stem cell differentiation, long non-coding RNAs (lncRNAs) orchestrate multilayered gene regulation through compartment-specific mechanisms. This review introduces a spatiotemporal framework linking lncRNA localization to epigenetic, transcriptional, and post-transcriptional control, and highlights emerging lncRNA-targeted therapies. By integrating mechanistic insights with therapeutic strategies, it redefines lncRNAs as dynamic spatial organizers of stem cell fate, offering new opportunities for regenerative medicine and precision therapy. |
| Publish Date |
2025-07-24 09:11 |
| Citation |
Li YH, Yao YN, Zhou SA, Wang Y. Regulation and intervention of stem cell differentiation by long non-coding RNAs: Mechanisms and therapeutic potential. World J Stem Cells 2025; 17(7): 107688 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i7/107688.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i7.107688 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
