BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
7/24/2025 9:11:32 AM | Browse: 71 | Download: 273
 |
Received |
|
2025-03-28 04:13 |
|
Peer-Review Started |
|
2025-03-28 04:13 |
|
First Decision by Editorial Office Director |
|
2025-04-09 12:28 |
|
Return for Revision |
|
2025-04-09 12:28 |
|
Revised |
|
2025-04-22 14:59 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2025-06-11 02:44 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-06-13 06:51 |
|
Articles in Press |
|
2025-06-13 06:51 |
|
Edit the Manuscript by Language Editor |
|
2025-06-18 19:03 |
|
Typeset the Manuscript |
|
2025-07-17 06:47 |
|
Publish the Manuscript Online |
|
2025-07-24 09:11 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Regulation and intervention of stem cell differentiation by long non-coding RNAs: Mechanisms and therapeutic potential
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ye-Hua Li, Yi-Ning Yao, Shen-Ao Zhou and Yang Wang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
32200755, 32200621 |
| Natural Science Foundation of Gansu Province |
23JRRA696 |
|
| Corresponding Author |
Yang Wang, PhD, School of Life Sciences, Fudan University, No. 2005 Songhu Road, Yangpu District, Shanghai 200438, China. w_yang@fudan.edu.cn |
| Key Words |
Long non-coding RNAs; Stem cell differentiation; MicroRNA sponges; Epigenetic regulation; Regenerative medicine; Delivery and precise targeting; Stem cell therapy |
| Core Tip |
As key regulators of stem cell differentiation, long non-coding RNAs (lncRNAs) orchestrate multilayered gene regulation through compartment-specific mechanisms. This review introduces a spatiotemporal framework linking lncRNA localization to epigenetic, transcriptional, and post-transcriptional control, and highlights emerging lncRNA-targeted therapies. By integrating mechanistic insights with therapeutic strategies, it redefines lncRNAs as dynamic spatial organizers of stem cell fate, offering new opportunities for regenerative medicine and precision therapy. |
| Publish Date |
2025-07-24 09:11 |
| Citation |
Li YH, Yao YN, Zhou SA, Wang Y. Regulation and intervention of stem cell differentiation by long non-coding RNAs: Mechanisms and therapeutic potential. World J Stem Cells 2025; 17(7): 107688 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i7/107688.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i7.107688 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
