Publication Name	World Journal of Hepatology
Manuscript ID	10769
Country	Italy

Received	2014-04-18 10:55
Peer-Review Started	2014-04-18 16:05
First Decision by Editorial Office Director
Return for Revision	2014-05-16 15:10
Revised	2014-06-12 07:48
Publication Fee Transferred
Second Decision by Editor	2014-06-27 17:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-06-27 17:59
Articles in Press	2014-06-27 18:16
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-22 17:27
Publish the Manuscript Online	2014-07-25 16:43

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	CEUS and Fibroscan in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis
Manuscript Source	Unsolicited Manuscript
All Author List	Sila Cocciolillo, Giustino Parruti and Leonardo Marzio
Funding Agency and Grant Number
Corresponding Author	Sila Cocciolillo, MD, Digestive Physiopathology Unit, Gabriele d’Annunzio University, Pescara Civic Hospital, Via Fonte Romana 8, 65124 Pescara, Italy. s_sila2000@yahoo.it
Key Words	Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Contrast-enhanced ultrasound; Fibroscan; Hepatic blood flow; Liver stiffness
Core Tip	The use of contrast-enhanced ultrasound (CEUS) assisted by dedicated software (Qontrast?) in combination with Fibroscan examination could provide a non-invasive tool to evaluate the level of fatty-liver disease. In this study, we found that there were reductions in portal and intra-parenchymal blood flow in patients affected by non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NASH), whereas liver stiffness was increased only in NASH patients. Qontrast?-assisted CEUS could be used to quantify early changes in intra-parenchymal liver flow before the onset of fibrosis.
Publish Date	2014-07-25 16:43
Citation	Cocciolillo S, Parruti G, Marzio L. CEUS and Fibroscan in nonalcoholic fatty liver disease and non-alcoholic steatohepatitis. World J Hepatol 2014; 6(7): 496-503
URL	http://www.wjgnet.com/1948-5182/full/v6/i7/496.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i7.496

Full Article (PDF)	WJH-6-496.pdf
Full Article (Word)	WJH-6-496.doc
Manuscript File	10769-Review.docx
Answering Reviewers	10769-Answering reviewers.pdf
Copyright License Agreement	10769-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	10769-Language certificate.pdf
Peer-review Report	10769-Peer review(s).pdf
Scientific Misconduct Check	10769-CrossCheck.jpg
Scientific Editor Work List	10769-Scientific editor work list.pdf