Publication Name	World Journal of Psychiatry
Manuscript ID	107696
Country	China

Received	2025-03-28 04:34
Peer-Review Started	2025-03-31 01:34
To Make the First Decision
Return for Revision	2025-04-08 13:10
Revised	2025-04-19 02:45
Second Decision	2025-06-16 02:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-23 10:53
Articles in Press	2025-06-23 10:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-07-22 02:38
Publish the Manuscript Online	2025-08-08 10:23

ISSN	2220-3206 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Neurosciences
Manuscript Type	Minireviews
Article Title	Interaction between the brain and multiple organ systems in schizophrenia
Manuscript Source	Invited Manuscript
All Author List	Jin Lin, Si-Tong Feng, Zi-Yao Wu, Lin-Rui Dong, Dong-Qing Yin, Hong Zhu, Hong-Xiao Jia and Yan-Zhe Ning
ORCID	Author(s) ORCID Number Yan-Zhe Ning http://orcid.org/0000-0002-6439-522X
Funding Agency and Grant Number	Funding Agency Grant Number Beijing Traditional Chinese Medicine Scientific and Technological Development Fund Project BJZYYB-2023-66 Beijing Natural Science Foundation 7212050 the Capital’s Funds for Health Improvement and Research 2020-4-2126
Corresponding Author	Yan-Zhe Ning, Beijing Key Laboratory of Mental Disorders, National Medical Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, No. 5 Ankang Hutong, Xicheng District, Beijing 100088, China. ningzy0923@mail.ccmu.edu.cn
Key Words	Schizophrenia; Brain-body interactions; Pathophysiological mechanisms; Multiple organic systems; Systemic integration
Core Tip	While existing reviews of schizophrenia focus primarily on central nervous system pathophysiology, this minireview uniquely highlights the growing evidence of interactions between the brain and peripheral organ systems, including the cardiovascular, pulmonary, hepatic, immune, and renal systems. It underscores the critical role of brain-organ interaction via the autonomic nervous system, endocrine system, and immune system in the pathophysiology of schizophrenia, providing new insights into its underlying mechanisms and potential therapeutic targets.
Publish Date	2025-08-08 10:23
Citation	<p>Lin J, Feng ST, Wu ZY, Dong LR, Yin DQ, Zhu H, Jia HX, Ning YZ. Interaction between the brain and multiple organ systems in schizophrenia. <i>World J Psychiatry</i> 2025; 15(8): 107696</p>
URL	https://www.wjgnet.com/2220-3206/full/v15/i8/107696.htm
DOI	https://dx.doi.org/10.5498/wjp.v15.i8.107696

Full Article (PDF)	WJP-15-107696-with-cover.pdf
Manuscript File	107696_Auto_Edited_074444.docx
Answering Reviewers	107696-answering-reviewers.pdf
Audio Core Tip	107696-audio.m4a
Conflict-of-Interest Disclosure Form	107696-conflict-of-interest-statement.pdf
Copyright License Agreement	107696-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	107696-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	107696-non-native-speakers.pdf
Peer-review Report	107696-peer-reviews.pdf
Scientific Misconduct Check	107696-scientific-misconduct-check.png
Scientific Editor Work List	107696-scientific-editor-work-list.pdf
CrossCheck Report	107696-crosscheck-report.pdf