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Articles Published Processes
8/12/2025 8:18:28 AM | Browse: 3 | Download: 12
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Received |
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2025-04-02 08:40 |
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Peer-Review Started |
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2025-04-07 01:13 |
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To Make the First Decision |
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Return for Revision |
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2025-04-22 03:17 |
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Revised |
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2025-05-01 16:39 |
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Second Decision |
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2025-06-24 02:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-24 08:07 |
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Articles in Press |
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2025-06-24 08:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-01 02:31 |
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Publish the Manuscript Online |
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2025-08-12 08:18 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Control Study |
| Article Title |
Clinical significance of differential plasma proteins levels in the diagnosis of epithelial ovarian cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Noha H Ibrahim, Mona S Abdellateif, Dina S Serag, Ahmed Laymouna, Mennatallah S Elaguizy and Radwa Marawan Abdel Halim |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mona S Abdellateif, MD, PhD, Department of Cancer Biology, National Cancer Institute, Cairo University, 1 Fom Elkhaligue, cairo 11796, Egypt. mona.sayed@nci.cu.edu.eg |
| Key Words |
Ovarian cancer; Human epididymis protein 4; Cancer antigen 125; Insulin-like growth factors-binding proteins 2; Thrombospondin 1 protein; Secreted phosphoprotein 1; Biomarkers |
| Core Tip |
Serum secreted phosphoprotein 1 (SPP1) can be a potential marker for the differentiation of patients with benign from those with malignant ovarian masses. insulin-like growth factors-binding proteins 2 (IGFBP2) and D-dimer could be potential markers for the diagnosis of patients with ovarian masses in relation to healthy controls. IGFBP2 could be a useful, sensitive diagnostic marker for epithelial ovarian cancer (EOC) patients. Also, combining SPP1 with cancer antigen 125 or thrombospondin 1 protein provides a high sensitivity (93.3%) and specificity (100%) for the detection of EOC patients. |
| Publish Date |
2025-08-12 08:18 |
| Citation |
<p>Ibrahim NH, Abdellateif MS, Serag DS, Laymouna A, Elaguizy MS, Halim RMA. Clinical significance of differential plasma proteins levels in the diagnosis of epithelial ovarian cancer. <i>World J Exp Med</i> 2025; 15(3): 107711</p> |
| URL |
https://www.wjgnet.com/2220-315X/full/v15/i3/107711.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v15.i3.107711 |
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