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Articles Published Processes
9/17/2025 8:57:34 AM | Browse: 444 | Download: 61
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Received |
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2025-03-28 07:09 |
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Peer-Review Started |
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2025-04-01 00:10 |
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To Make the First Decision |
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Return for Revision |
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2025-04-14 04:07 |
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Revised |
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2025-04-20 21:55 |
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Second Decision |
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2025-06-10 02:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-10 11:29 |
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Articles in Press |
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2025-06-10 11:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-18 00:32 |
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Publish the Manuscript Online |
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2025-09-17 08:57 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Cardamom extract: An effective weapon in prevention of cardiorenal syndrome induced in rats by cisplatin and high-fat diet
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Doha Mohamed, Ibrahim Hamed and Hoda B Mabrok |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Research Centre, Egypt |
13050203 |
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| Corresponding Author |
Doha Mohamed, Additional Professor, PhD, Professor, Department of Nutrition and Food Science, National Research Centre, 33 El Buhouth St, Ad Doqi, Dokki, Cairo Governorate 12622, Cairo 12622, Al Qāhirah, Egypt. dohaabdomohamed@gmail.com |
| Key Words |
Cardiorenal syndrome; Cardamom extract; Hippo signaling pathway; Oxidative stress; Inflammatory markers; Phenolic compounds |
| Core Tip |
In this study, cardiorenal syndrome (CRS) was experimentally induced in rats using a high-fat diet and cisplatin. The protective effects of crude ethanol extract (CEE) of cardamom were evaluated through comprehensive biochemical analyses. The potential mechanistic role of CEE phenolics was explored via molecular docking with the Hippo signaling pathway. The findings suggest that CEE, as a phenolic-rich dietary supplement, may protect against CRS by reducing inflammation and oxidative stress, and by targeting components of the Hippo pathway. |
| Publish Date |
2025-09-17 08:57 |
| Citation |
<p>Mohamed D, Hamed I, Mabrok HB. Cardamom extract: An effective weapon in prevention of cardiorenal syndrome induced in rats by cisplatin and high-fat diet. <i>World J Nephrol</i> 2025; 14(3): 107736</p> |
| URL |
https://www.wjgnet.com/2220-6124/full/v14/i3/107736.htm |
| DOI |
https://dx.doi.org/10.5527/wjn.v14.i3.107736 |
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