Publication Name	World Journal of Gastroenterology
Manuscript ID	10774
Country	Germany

Received	2014-04-18 21:13
Peer-Review Started	2014-04-19 17:57
To Make the First Decision	2014-05-13 20:03
Return for Revision	2014-05-21 08:27
Revised	2014-06-08 00:00
Second Decision	2014-07-11 17:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-07-11 17:12
Articles in Press	2014-07-11 17:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-17 10:24
Publish the Manuscript Online	2015-01-06 09:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Motility patterns of ex vivo intestine segments depend on perfusion mode
Manuscript Source	Unsolicited Manuscript
All Author List	Dominik Schreiber, Viktor Jost, Michael Bischof, Kristina Seebach, Wim JEP Lammers, Rees Douglas and Karl-Herbert Schäfer
Funding Agency and Grant Number
Corresponding Author	Karl-Herbert Schäfer, MD, Enteric Nervous System Group, University of Applied Sciences Kaiserslautern, 1 Amerikastrasse, Zweibrücken 66482, Germany. karl-herbert.schaefer@hs-kl.de
Key Words	Small intestine; Motility; Organ perfusion; Pharmacological testing; Visualization
Core Tip	Perfused intestinal segments can be used as a pharmacological model in order to test drugs acting on motility and gastrointestinal physiology. Different motility patterns can be distinguished using visualization and appropriate software tools. In order to use intestinal segments for pharmacological testing it is important to know which factors affect intestinal motility. Motility measurement and characterization of motility pattern in the ex vivo system is much easier compared to in vivo measurements. The main disadvantage of the ex vivo system is its limited stability. Therefore longer ex vivo times are desirable. In this study we could demonstrate effects of different perfusion media on tissue viability and visualize motility in response to perfusion conditions.
Publish Date	2015-01-06 09:08
Citation	Schreiber D, Jost V, Bischof M, Seebach K, Lammers WJEP, Douglas R, Schäfer KH. Motility patterns of ex vivo intestine segments depend on perfusion mode. World J Gastroenterol 2014; 20(48): 18216-18227
URL	http://www.wjgnet.com/1007-9327/full/v20/i48/18216.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i48.18216

Full Article (PDF)	WJG-20-18216.pdf
Full Article (Word)	WJG-20-18216.doc
Manuscript File	10774-Review.doc
Answering Reviewers	10774-Answering reviewers.pdf
Copyright License Agreement	10774-Copyright assignment.pdf
Peer-review Report	10774-Peer review.pdf
Scientific Misconduct Check	10774-CrossCheck.jpg
Scientific Editor Work List	10774-Scientific editor work list.pdf