Publication Name	World Journal of Diabetes
Manuscript ID	107779
Country	China

Received	2025-03-30 10:18
Peer-Review Started	2025-03-31 00:23
To Make the First Decision
Return for Revision	2025-04-08 09:27
Revised	2025-04-21 07:16
Second Decision	2025-06-13 02:53
Accepted by Journal Editor-in-Chief	2025-06-17 02:54
Accepted by Executive Editor-in-Chief	2025-06-25 06:51
Articles in Press	2025-06-25 06:51
Publication Fee Transferred	2025-04-22 07:59
Edit the Manuscript by Language Editor	2025-07-08 19:54
Typeset the Manuscript	2025-08-04 02:50
Publish the Manuscript Online	2025-08-14 10:52

ISSN	1948-9358 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Electroacupuncture with different current intensities can improve gastrointestinal motility in diabetic gastroparesis via vagal and sympathetic pathways
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Wen Tang, You Zhang, Jin Zhou, Yu-Ting Peng, Yan Zi, Yan-Rong Wei and Zeng-Hui Yue
ORCID	Author(s) ORCID Number Zeng-Hui Yue http://orcid.org/0000-0002-9234-3056
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82205298 Natural Science Foundation of Hunan Province 2023JJ30462 Hunan Provincial Department of Science and Technology 2023SK2045 Hunan Provincial Department of Science and Technology 22JBZ007 Hunan Provincial Department of Science and Technology Z2023XJYQ07 Hunan Provincial Department of Science and Technology B2024007 Hunan Provincial Department of Science and Technology Z2023JB01 2024 Graduate Innovation Topics 2024CX031
Corresponding Author	Zeng-Hui Yue, Postdoc, Professor, College of Acupuncture, Massage and Rehabilitation, Hunan University of Chinese Medicine, No. 300 Bachelor Road, Yuelu District, Changsha 410208, Hunan Province, China. yue5381316@126.com
Key Words	Diabetic gastroparesis; Electroacupuncture; Current intensity; Vagus nerve; Sympathetic nerve
Core Tip	Electroacupuncture (EA) repairs interstitial cells of Cajal network by upregulating smooth muscle-related factors Rho guanine nucleotide binding protein A and Rho-associated coiled-coil forming protein kinase, significantly enhances gastric emptying, restores gastric slow wave rhythms, and improves smooth muscle structure. We verified that the mechanism of EA treatment may be related to the activation of the vagal-cholinergic pathway by 0.5 mA current intensity EA and the modulation of the sympathoadrenergic pathway by 3 mA current intensity EA and ultimately the promotion of gastrointestinal motility.
Publish Date	2025-08-14 10:52
Citation	<p>Tang YW, Zhang Y, Zhou J, Peng YT, Zi Y, Wei YR, Yue ZH. Electroacupuncture with different current intensities can improve gastrointestinal motility in diabetic gastroparesis via vagal and sympathetic pathways. <i>World J Diabetes</i> 2025; 16(8): 107779</p>
URL	https://www.wjgnet.com/1948-9358/full/v16/i8/107779.htm
DOI	https://dx.doi.org/10.4239/wjd.v16.i8.107779

Full Article (PDF)	WJD-16-107779-with-cover.pdf
The ARRIVE Guidelines	107779-The-ARRIVE-Guidelines.pdf
Manuscript File	107779_Auto_Edited_024118.docx
Answering Reviewers	107779-answering-reviewers.pdf
Audio Core Tip	107779-audio.mp3
Biostatistics Review Certificate	107779-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	107779-conflict-of-interest-statement.pdf
Copyright License Agreement	107779-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	107779-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	107779-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	107779-non-native-speakers.pdf
Peer-review Report	107779-peer-reviews.pdf
Journal Editor-in-Chief Review Report	107779-journal-editor-in-chief.pdf
Scientific Misconduct Check	107779-scientific-misconduct-check.png
Scientific Editor Work List	107779-scientific-editor-work-list.pdf
CrossCheck Report	107779-crosscheck-report.pdf