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8/27/2025 9:21:08 AM | Browse: 40 | Download: 59
Publication Name World Journal of Hepatology
Manuscript ID 107803
Country China
Received
2025-04-01 14:24
Peer-Review Started
2025-04-10 09:14
To Make the First Decision
Return for Revision
2025-04-23 11:18
Revised
2025-05-06 13:40
Second Decision
2025-07-07 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-07 07:42
Articles in Press
2025-07-07 07:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-15 03:07
Publish the Manuscript Online
2025-08-27 09:21
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Copper and hepatic lipid dysregulation: Mechanisms and implications
Manuscript Source Invited Manuscript
All Author List Dong-Jing Gao, Tao Zeng, Yu-Tian Chong and Xin-Hua Li
ORCID
Author(s) ORCID Number
Yu-Tian Chong http://orcid.org/0000-0001-8215-4393
Xin-Hua Li http://orcid.org/0000-0002-6748-9803
Funding Agency and Grant Number
Corresponding Author Xin-Hua Li, PhD, Professor, Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou 510630, Guangdong Province, China. lixinh8@mail.sysu.edu.cn
Key Words Copper; Hepatic steatosis; Mechanism; Metabolic dysfunction-associated steatotic liver disease; Wilson's disease
Core Tip Hepatic steatosis diseases are strongly associated with copper, and it has been shown that copper levels promote hepatic fat synthesis or lipolysis by triggering different mechanisms, which is extremely important for unravelling the molecular mechanisms of hepatic steatosis in diseases such as metabolic dysfunction-associated steatotic liver disease and Wilson's disease. This article reviews the potential mechanisms of copper-induced hepatic lipid dysregulation and explores new therapeutic targets for hepatic steatosis diseases.
Publish Date 2025-08-27 09:21
Citation <p>Gao DJ, Zeng T, Chong YT, Li XH. Copper and hepatic lipid dysregulation: Mechanisms and implications. <i>World J Hepatol</i> 2025; 17(8): 107803</p>
URL https://www.wjgnet.com/1948-5182/full/v17/i8/107803.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i8.107803
Full Article (PDF) WJH-17-107803-with-cover.pdf
Manuscript File 107803_Auto_Edited_074347.docx
Answering Reviewers 107803-answering-reviewers.pdf
Audio Core Tip 107803-audio.mp3
Conflict-of-Interest Disclosure Form 107803-conflict-of-interest-statement.pdf
Copyright License Agreement 107803-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 107803-non-native-speakers.pdf
Supplementary Material 107803-supplementary-material.pdf
Peer-review Report 107803-peer-reviews.pdf
Scientific Misconduct Check 107803-scientific-misconduct-check.png
Scientific Editor Work List 107803-scientific-editor-work-list.pdf
CrossCheck Report 107803-crosscheck-report.pdf