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Articles Published Processes
9/24/2025 9:01:54 AM | Browse: 61 | Download: 26
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Received |
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2025-03-31 08:24 |
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Peer-Review Started |
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2025-03-31 08:24 |
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To Make the First Decision |
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Return for Revision |
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2025-04-28 09:05 |
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Revised |
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2025-05-11 16:30 |
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Second Decision |
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2025-07-11 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-11 07:52 |
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Articles in Press |
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2025-07-11 07:52 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-07-17 05:22 |
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Typeset the Manuscript |
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2025-07-31 03:39 |
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Publish the Manuscript Online |
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2025-09-24 09:01 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Review |
| Article Title |
Watch and wait in locally advanced rectal cancer: Evolution, current evidence, and future directions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Andrés García-Fernández, Pilar del Pozo-Elso, Arantxa Villadóniga-Sánchez, Raquel Martínez and Miguel Suarez |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Andrés García-Fernández, MD, Department of General Surgery, Virgen de la Luz Hospital, Calle Hermandad de Donantes de Sangre, 1, Cuenca 16002, Castille-La Mancha, Spain. angarciafernandez@sescam.jccm.es |
| Key Words |
Locally advanced rectal cancer; Watch and wait; Total neoadjuvant therapy; Organ preserving therapy; Target tailored therapy |
| Core Tip |
The management of locally advanced rectal cancer has undergone major advancements, shifting toward more personalized and less invasive strategies. This review explores key innovations, including the watch and wait approach for clinical complete responders, the total neoadjuvant therapy paradigm, and the expansion of minimally invasive surgical techniques. Additionally, targeted therapies and immunotherapy are emerging as promising options. These advancements aim to improve survival while preserving organ function and minimizing morbidity. Future research should focus on optimizing patient selection and long-term outcomes, ensuring that novel therapeutic strategies continue to enhance cancer care. |
| Publish Date |
2025-09-24 09:01 |
| Citation |
<p>García-Fernández A, del Pozo-Elso P, Villadóniga-Sánchez A, Martínez R, Suarez M. Watch and wait in locally advanced rectal cancer: Evolution, current evidence, and future directions. <i>World J Gastrointest Surg</i> 2025; 17(9): 107831</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i9/107831.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i9.107831 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
