Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	107842
Country	United States

Received	2025-03-30 09:49
Peer-Review Started	2025-03-30 09:49
To Make the First Decision
Return for Revision	2025-04-03 02:47
Revised	2025-05-11 06:58
Second Decision	2025-08-22 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-22 09:07
Articles in Press	2025-08-22 09:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-10-20 09:11
Publish the Manuscript Online	2025-10-31 15:02

ISSN	2219-2808 (online)
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Category	Hematology
Manuscript Type	Case Report
Article Title	What should be investigated in delayed umbilical cord separation: Two case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Dhiaedin A Khiati and Sureyya Savasan
ORCID	Author(s) ORCID Number Dhiaedin A Khiati http://orcid.org/0000-0002-1869-0519 Sureyya Savasan http://orcid.org/0000-0001-7138-3027
Funding Agency and Grant Number
Corresponding Author	Sureyya Savasan, Professor, Department of Hematology Oncology, Chilrdren's Hospital of Michigan, 3901 Beaubien Blvd., Detroit, MI 48201, United States. savas1s@cmich.edu
Key Words	Factor XIII deficiency; Leukocyte adhesion deficiency; Urachal remnants; Delayed umbilical cord separation; Case report
Core Tip	Patients with delayed umbilical cord separation (UCS) are often referred to Hematology/Oncology for investigation of possible Leucocyte adhesion deficiency (LAD) and/or factor XIII deficiency. We highlight the presence of another yet often overlooked association with delayed UCS, urachal remnants (UR) and therefore, suggest an abdominal ultrasound if any investigation is sought. Moreover, neither LAD nor factor XIII testing should be conducted routinely at the time of delayed UCS documentation, nor in the long term in cases without infections.
Publish Date	2025-10-31 15:02
Citation	<p>Khiati DA, Savasan S. What should be investigated in delayed umbilical cord separation: Two case reports. <i>World J Clin Pediatr</i> 2025; 14(4): 107842</p>
URL	https://www.wjgnet.com/2219-2808/full/v14/i4/107842.htm
DOI	https://dx.doi.org/10.5409/wjcp.v14.i4.107842

Full Article (PDF)	WJCP-14-107842-with-cover.pdf
CARE Checklist–2016	107842-CARE-Checklist-2016.pdf
Manuscript File	107842_Auto_Edited_024221.docx
Answering Reviewers	107842-answering-reviewers.pdf
Audio Core Tip	107842-audio.m4a
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Peer-review Report	107842-peer-reviews.pdf
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Scientific Editor Work List	107842-scientific-editor-work-list.pdf
CrossCheck Report	107842-crosscheck-report.pdf