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9/11/2025 9:42:00 AM | Browse: 241 | Download: 66
Publication Name World Journal of Diabetes
Manuscript ID 107871
Country China
Received
2025-03-30 10:34
Peer-Review Started
2025-04-08 09:01
To Make the First Decision
Return for Revision
2025-07-02 08:23
Revised
2025-07-13 17:37
Second Decision
2025-08-13 05:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-20 09:47
Articles in Press
2025-08-20 09:47
Publication Fee Transferred
2025-07-17 15:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-03 09:52
Publish the Manuscript Online
2025-09-11 09:42
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Womens Studies
Manuscript Type Meta-Analysis
Article Title Efficacy of inositol supplementation in the prevention and treatment of gestational diabetes mellitus: A meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Ru-Tong Wang, Ying-Qi Feng, Meng-Yao Wang, Yan-Hong Wei, Yu-Jun Huang, Yu-Jia Guo, Xuan Liu, Xiao-Can Lei, Kong-Wei Huang and Hua Huang
ORCID
Author(s) ORCID Number
Kong-Wei Huang http://orcid.org/0000-0002-7761-9958
Funding Agency and Grant Number
Funding Agency Grant Number
the Natural Science Foundation of Guangxi in China 2024GXNSFAA010444
Doctoral Scientific Research Start-up Foundation of University of South China 5525QD005
Hunan Province Innovation and Entrepreneurship Training Program for College Students S202410555233
Corresponding Author Hua Huang, Department of Embryology laboratory, Reproductive Hospital of Guangxi Zhuang Autonomous Region, No.3 Longyuan Road, Qingxiu District, Nanning 533000, Guangxi Zhuang Autonomous Region, China. hh86168263@163.com
Key Words Meta-analysis; Pregnancy outcomes; Gestational diabetes mellitus; D-chiro inositol; Myo-inositol
Core Tip This meta-analysis reviews evidence on using inositol supplements to prevent and treat gestational diabetes mellitus (GDM). Findings show it significantly lowers GDM rates, fasting blood sugar, and the risk of bad pregnancy outcomes. This suggests inositol is a safe and effective option. Specifically, myo-inositol supplements reduced new GDM cases by 63% and improved glucose tolerance test results. They also decreased chances of preterm birth and pregnancy-induced high blood pressure. While inositol works well for prevention in high-risk women, we need more trials to confirm its treatment benefits for existing GDM. Therefore, clinicians can consider inositol as a preventive measure early in pregnancy for women with risk factors.
Publish Date 2025-09-11 09:42
Citation <p>Wang RT, Feng YQ, Wang MY, Wei YH, Huang YJ, Guo YJ, Liu X, Lei XC, Huang KW, Huang H. Efficacy of inositol supplementation in the prevention and treatment of gestational diabetes mellitus: A meta-analysis. <i>World J Diabetes</i> 2025; 16(9): 107871</p>
URL https://www.wjgnet.com/1948-9358/full/v16/i9/107871.htm
DOI https://dx.doi.org/10.4239/wjd.v16.i9.107871
Full Article (PDF) WJD-16-107871-with-cover.pdf
PRISMA 2009 Checklist 107871-PRISMA-2009-Checklist.pdf
Manuscript File 107871_Auto_Edited_025406.docx
Answering Reviewers 107871-answering-reviewers.pdf
Audio Core Tip 107871-audio.mp3
Conflict-of-Interest Disclosure Form 107871-conflict-of-interest-statement.pdf
Copyright License Agreement 107871-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 107871-non-native-speakers.pdf
Supplementary Material 107871-supplementary-material.pdf
Peer-review Report 107871-peer-reviews.pdf
Scientific Misconduct Check 107871-scientific-misconduct-check.png
Scientific Editor Work List 107871-scientific-editor-work-list.pdf
CrossCheck Report 107871-crosscheck-report.pdf