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Articles Published Processes
10/24/2025 6:10:10 AM | Browse: 6 | Download: 23
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Received |
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2025-03-30 11:52 |
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Peer-Review Started |
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2025-03-30 11:52 |
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First Decision by Editorial Office Director |
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2025-05-17 07:30 |
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Return for Revision |
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2025-05-17 07:30 |
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Revised |
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2025-05-29 20:38 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-09-04 02:51 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-09-04 08:44 |
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Articles in Press |
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2025-09-04 08:44 |
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Edit the Manuscript by Language Editor |
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2025-09-09 05:22 |
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Typeset the Manuscript |
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2025-10-17 02:00 |
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Publish the Manuscript Online |
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2025-10-24 06:10 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Circulating tumor DNA in biliary tract cancers: A review of current applications
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maria Fernanda Teixeira, Mitesh Borad and Pedro Luiz Serrano Uson Junior |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Pedro Luiz Serrano Uson Junior, Associate Professor, Full Professor, MD, Senior Research Fellow, Center for Personalized Medicine, Hospital Israelita Albert Einstein, Hospital Israelita Albert Einstein, 627/701 Av. Albert Einstein, Morumbi, Sao Paulo, CEP 05651-901, Brazil. pedroluiz_uson@hotmail.com., Sao Paulo 05651901, Brazil. pedroluiz_uson@hotmail.com |
| Key Words |
Biliary tract cancer; Circulating tumor DNA; Genomic profiling; Bile-derived circulating tumor DNA; Clonal evolution; Mutation clearance |
| Core Tip |
Molecular profiling of biliary tract cancers has significantly transformed the management of these diseases by paving the way for a broader range of therapeutic options, leading to improved survival outcomes. Given the scarcity of tissue, circulating tumor DNA (ctDNA) has emerged as a promising non-invasive biomarker for genomic profiling, with high concordance with genomic alterations identified in tissue, particularly in therapy-naïve and metastasis-derived samples. Furthermore, ctDNA has a strong prognostic association and is an effective strategy for monitoring patients during systemic treatment. |
| Publish Date |
2025-10-24 06:10 |
| Citation |
Teixeira MF, Borad M, Serrano Uson Junior PL. Circulating tumor DNA in biliary tract cancers: A review of current applications. World J Clin Oncol 2025; 16(10): 107875 |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i10/107875.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i10.107875 |
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