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9/24/2025 9:02:04 AM | Browse: 73 | Download: 36
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 107966
Country China
Received
2025-04-02 02:07
Peer-Review Started
2025-04-02 02:08
To Make the First Decision
Return for Revision
2025-04-16 09:46
Revised
2025-06-25 08:23
Second Decision
2025-07-31 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-31 07:00
Articles in Press
2025-07-31 07:00
Publication Fee Transferred
2025-06-30 07:46
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-04 06:00
Publish the Manuscript Online
2025-09-24 09:02
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Survival benefit of primary tumor resection in pancreatic neuroendocrine tumors with unresectable liver metastases: A meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Jie Gong, Ben-Jian Gao and Ze-Hua Lei
ORCID
Author(s) ORCID Number
Ze-Hua Lei http://orcid.org/0000-0003-3335-1803
Funding Agency and Grant Number
Corresponding Author Ze-Hua Lei, MD, Professor, Department of Hepatopancreatobiliary Surgery, The People’s Hospital of Leshan, No. 238 Baita Street, Leshan 614000, Sichuan Province, China. leitsehua@126.com
Key Words Primary tumor resection; Pancreatic neuroendocrine tumors; Liver metastases; Overall survival; Surveillance, Epidemiology, and End Results database
Core Tip This study comprehensively evaluates the impact of primary tumor resection (PTR) on survival in patients with pancreatic neuroendocrine tumors and unresectable liver metastases. Our meta-analysis, involving 16 studies and 8761 patients, demonstrates that PTR significantly improves overall survival. Analysis of the Surveillance, Epidemiology, and End Results database further supports these findings, showing consistent survival benefits across different tumor differentiation levels. However, PTR’s effect on tumor grading remains unclear, highlighting the need for further large-scale prospective studies to refine surgical approaches for this patient population.
Publish Date 2025-09-24 09:02
Citation <p>Gong J, Gao BJ, Lei ZH. Survival benefit of primary tumor resection in pancreatic neuroendocrine tumors with unresectable liver metastases: A meta-analysis. <i>World J Gastrointest Surg</i> 2025; 17(9): 107966</p>
URL https://www.wjgnet.com/1948-9366/full/v17/i9/107966.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i9.107966
Full Article (PDF) WJGS-17-107966-with-cover.pdf
PRISMA 2009 Checklist 107966-PRISMA-2009-Checklist.pdf
Manuscript File 107966_Auto_Edited_071630.docx
Answering Reviewers 107966-answering-reviewers.pdf
Audio Core Tip 107966-audio.wav
Biostatistics Review Certificate 107966-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 107966-conflict-of-interest-statement.pdf
Copyright License Agreement 107966-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 107966-non-native-speakers.pdf
Supplementary Material 107966-supplementary-material.pdf
Peer-review Report 107966-peer-reviews.pdf
Scientific Misconduct Check 107966-scientific-misconduct-check.png
Scientific Editor Work List 107966-scientific-editor-work-list.pdf
CrossCheck Report 107966-crosscheck-report.pdf