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10/31/2025 3:02:47 PM | Browse: 19 | Download: 89
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 107974
Country India
Received
2025-04-03 03:16
Peer-Review Started
2025-04-03 03:16
First Decision by Editorial Office Director
2025-04-15 02:28
Return for Revision
2025-04-15 02:28
Revised
2025-04-21 09:28
Publication Fee Transferred
Second Decision by Editor
2025-06-05 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-06-07 05:12
Articles in Press
2025-06-07 05:12
Edit the Manuscript by Language Editor
2025-06-11 21:49
Typeset the Manuscript
2025-08-07 15:34
Publish the Manuscript Online
2025-10-31 15:02
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Minireviews
Article Title Neonatal and pediatric sepsis: Microbiological insights, diagnostic innovations, and antimicrobial challenges
Manuscript Source Invited Manuscript
All Author List Basavraj S Nagoba, Shree V Dhotre, Mahesh N Sonar, Sachin S Mumbre, Ajay M Gavkare and Pradnya S Dhotre
ORCID
Author(s) ORCID Number
Basavraj S Nagoba http://orcid.org/0000-0001-5625-3777
Shree V Dhotre http://orcid.org/0000-0003-0786-818X
Sachin S Mumbre http://orcid.org/0000-0002-9169-6001
Ajay M Gavkare http://orcid.org/0000-0003-4711-5596
Funding Agency and Grant Number
Corresponding Author Basavraj S Nagoba, PhD, Professor, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Vishwanathpuram, Ambajogai Road, Latur 413531, Maharashtra, India. dr_bsnagoba@yahoo.com
Key Words Neonatal infections; AI in diagnostics; Microbiome; Antimicrobial stewardship; Neonatal intensive care unit; Sepsis biomarkers
Core Tip Neonatal and pediatric sepsis is a major contributor to global child mortality, with significant challenges in timely and accurate diagnosis. Traditional blood culture methods have limitations, necessitating advancements in molecular diagnostics and biomarker-based approaches. Emerging technologies such as metagenomic sequencing and artificial intelligence -driven diagnostic tools offer promising solutions for rapid pathogen identification. Antimicrobial resistance continues to complicate treatment, making antimicrobial stewardship programs crucial in pediatric healthcare. This review highlights microbiological insights, diagnostic advancements, antimicrobial resistance mechanisms, combination therapy strategies, and approaches to improving early detection and outcomes in pediatric sepsis.
Publish Date 2025-10-31 15:02
Citation

Nagoba BS, Dhotre SV, Sonar MN, Mumbre SS, Gavkare AM, Dhotre PS. Neonatal and pediatric sepsis: Microbiological insights, diagnostic innovations, and antimicrobial challenges. World J Clin Pediatr 2025; 14(4): 107974

URL https://www.wjgnet.com/2219-2808/full/v14/i4/107974.htm
DOI https://dx.doi.org/10.5409/wjcp.v14.i4.107974
Full Article (PDF) WJCP-14-107974-with-cover.pdf
Manuscript File 107974_Auto_Edited_083016.docx
Answering Reviewers 107974-answering-reviewers.pdf
Audio Core Tip 107974-audio.mp3
Conflict-of-Interest Disclosure Form 107974-conflict-of-interest-statement.pdf
Copyright License Agreement 107974-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 107974-non-native-speakers.pdf
Peer-review Report 107974-peer-reviews.pdf
Scientific Misconduct Check 107974-scientific-misconduct-check.png
Scientific Editor Work List 107974-scientific-editor-work-list.pdf
CrossCheck Report 107974-crosscheck-report.pdf