BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/24/2025 3:48:38 AM | Browse: 9 | Download: 34
 |
Received |
|
2025-04-10 01:37 |
|
Peer-Review Started |
|
2025-04-10 01:37 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2025-05-13 12:25 |
|
Revised |
|
2025-06-12 09:24 |
|
Second Decision |
|
2025-08-22 09:49 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2025-08-29 10:42 |
|
Articles in Press |
|
2025-08-29 10:42 |
|
Publication Fee Transferred |
|
2025-06-19 10:05 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-09-06 15:05 |
|
Publish the Manuscript Online |
|
2025-09-24 03:48 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dermatology |
| Manuscript Type |
Basic Study |
| Article Title |
Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hyunjun Ahn, Ho-Seong Han and Kye-Ho Lee |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Kye-Ho Lee, PhD, Stem Cell Treatment and Research Institute, Bio-Beauty & Health Company, No. 72 UN Village Gil, Yongsan-gu, Seoul 04420, South Korea. msoh@stc365.com |
| Key Words |
Skin aging; Mesenchymal stem cell; Umbilical cord-derived mesenchymal stem cell; Mesenchymal stem cell-conditioned medium; Treating skin |
| Core Tip |
Umbilical cord-derived mesenchymal stem cell-conditioned medium (UCMSC-CM) contains higher levels of effective factors than adipose-derived mesenchymal stem cell-conditioned medium, enhancing skin fibroblast proliferation and inhibiting melanin production in vitro. It promotes skin regeneration more effectively than adipose-derived mesenchymal stem cell-conditioned medium in aged skin in vivo. Subcutaneous injection of UCMSC-CM was the most effective method for promoting skin regeneration in aged skin in vivo. A non-clinical safety evaluation indicated that UCMSC-CM is a safe substance. These findings highlight UCMSC-CM as a promising and effective treatment for skin aging. |
| Publish Date |
2025-09-24 03:48 |
| Citation |
<p>Ahn H, Han HS, Lee KH. Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging. <i>World J Stem Cells</i> 2025; 17(9): 108049</p> |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i9/108049.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i9.108049 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
