BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/24/2025 3:48:38 AM | Browse: 81 | Download: 332
 |
Received |
|
2025-04-10 01:37 |
|
Peer-Review Started |
|
2025-04-10 01:37 |
|
First Decision by Editorial Office Director |
|
2025-05-13 12:25 |
|
Return for Revision |
|
2025-05-13 12:25 |
|
Revised |
|
2025-06-12 09:24 |
|
Publication Fee Transferred |
|
2025-06-19 10:05 |
|
Second Decision by Editor |
|
2025-08-22 09:49 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-08-29 10:42 |
|
Articles in Press |
|
2025-08-29 10:42 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-09-06 15:05 |
|
Publish the Manuscript Online |
|
2025-09-24 03:48 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dermatology |
| Manuscript Type |
Basic Study |
| Article Title |
Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hyunjun Ahn, Ho-Seong Han and Kye-Ho Lee |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Kye-Ho Lee, PhD, Stem Cell Treatment and Research Institute, Bio-Beauty & Health Company, No. 72 UN Village Gil, Yongsan-gu, Seoul 04420, South Korea. msoh@stc365.com |
| Key Words |
Skin aging; Mesenchymal stem cell; Umbilical cord-derived mesenchymal stem cell; Mesenchymal stem cell-conditioned medium; Treating skin |
| Core Tip |
Umbilical cord-derived mesenchymal stem cell-conditioned medium (UCMSC-CM) contains higher levels of effective factors than adipose-derived mesenchymal stem cell-conditioned medium, enhancing skin fibroblast proliferation and inhibiting melanin production in vitro. It promotes skin regeneration more effectively than adipose-derived mesenchymal stem cell-conditioned medium in aged skin in vivo. Subcutaneous injection of UCMSC-CM was the most effective method for promoting skin regeneration in aged skin in vivo. A non-clinical safety evaluation indicated that UCMSC-CM is a safe substance. These findings highlight UCMSC-CM as a promising and effective treatment for skin aging. |
| Publish Date |
2025-09-24 03:48 |
| Citation |
Ahn H, Han HS, Lee KH. Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging. World J Stem Cells 2025; 17(9): 108049 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i9/108049.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i9.108049 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
