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Articles Published Processes
10/31/2025 3:02:52 PM | Browse: 1 | Download: 1
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Received |
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2025-04-08 14:55 |
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Peer-Review Started |
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2025-04-08 14:55 |
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To Make the First Decision |
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Return for Revision |
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2025-05-20 08:24 |
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Revised |
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2025-05-23 21:48 |
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Second Decision |
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2025-08-07 02:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-08 09:49 |
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Articles in Press |
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2025-08-08 09:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-20 01:48 |
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Publish the Manuscript Online |
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2025-10-31 15:02 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Case Control Study |
| Article Title |
Serum resistin levels in pediatric familial Mediterranean fever: Potential biomarker for inflammatory activity
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Lamia M Morad, Eman Elsaadany, Shaima S Qassem, Maha S Elnady, Amira Ahmed Abdel-Kareem and Mohammed Al-Beltagi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammed Al-Beltagi, Department of Pediatrics, Faculty of Medicine, Tanta University, 1 Hassan Radwan Street, Tanta 31511, Algharbia, Egypt. mbelrem@hotmail.com |
| Key Words |
Familial Mediterranean fever; Resistin; Inflammatory biomarkers; Acute phase response; Pediatric autoinflammatory disease; Serum inflammatory markers; Cytokine regulation |
| Core Tip |
This study demonstrates that serum resistin levels are significantly elevated in patients with Familial Mediterranean Fever, particularly during acute attacks, and are closely associated with key inflammatory markers. Elevated resistin levels correlate with specific MEFV genotypes, such as E148Q and M694V, which are associated with more severe disease phenotypes. These findings suggest that resistin could be a valuable biomarker for diagnosing Familial Mediterranean Fever, monitoring disease activity, and assessing clinical severity. The study highlights the potential of resistin-targeted therapies and emphasizes the need for further research to explore their clinical applications in familial Mediterranean fever management. |
| Publish Date |
2025-10-31 15:02 |
| Citation |
<p>Morad LM, Elsaadany E, Qassem SS, Elnady MS, Abdel-Kareem AA, Al-Beltagi M. Serum resistin levels in pediatric familial Mediterranean fever: Potential biomarker for inflammatory activity. <i>World J Clin Pediatr</i> 2025; 14(4): 108068</p> |
| URL |
https://www.wjgnet.com/2219-2808/full/v14/i4/108068.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v14.i4.108068 |
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