| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Comparison between short-course and long-course antimicrobial treatments for acute cholangitis with gram-positive coccus bacteremia after endoscopic retrograde cholangiopancreatography
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yuntae Kim, Kazuhiro Ishikawa, Kenji Nakamura, Hikaru Ikusaka, Ryohsuke Yokosuka, Tomohiro Yamazaki, Yuichiro Suzuki, Shuhei Okuyama, Koichi Takagi and Katsuyuki Fukuda |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yuntae Kim, MD, Department of Gastroenterology, St. Luke's International Hospital, 9-1 Akashi-Cho, Chuo-Ku, Tokyo 104-8560, Japan. yunte.soccer.05@gmail.com |
| Key Words |
Acute cholangitis; Antibiotic; Short-course; Long-course; Antimicrobial; Treatment duration; Gram-positive coccus bacteremia; Endoscopic retrograde cholangiopancreatography |
| Core Tip |
The optimal duration of antimicrobial treatment for acute cholangitis with gram-positive coccus bacteremia has not been well investigated. The Tokyo Guidelines 2018 recommended at least 14 days of treatment, citing the potential risk of infective endocarditis. However, the actual risk appears to be low, and a discrepancy with real-world practice has therefore been proposed. This study evaluated mortality, relapse, reinfection with the same organism, and length of hospital stay between the short-course treatment (SCT) and long-course treatment groups. No significant differences were observed in the treatment outcomes; however, the length of hospital stay tended to be shorter in the SCT group. |
| Publish Date |
2025-06-26 07:27 |
| Citation |
<p>Kim Y, Ishikawa K, Nakamura K, Ikusaka H, Yokosuka R, Yamazaki T, Suzuki Y, Okuyama S, Takagi K, Fukuda K. Comparison between short-course and long-course antimicrobial treatments for acute cholangitis with gram-positive coccus bacteremia after endoscopic retrograde cholangiopancreatography. <i>World J Hepatol</i> 2025; 17(6): 108100</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i6/108100.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i6.108100 |
