Publication Name	World Journal of Gastroenterology
Manuscript ID	10811
Country	China

Received	2014-04-21 09:13
Peer-Review Started	2014-04-21 13:31
First Decision by Editorial Office Director
Return for Revision	2014-05-21 08:26
Revised	2014-06-08 00:00
Publication Fee Transferred
Second Decision by Editor	2014-07-11 17:03
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-07-11 17:15
Articles in Press	2014-07-11 17:34
Edit the Manuscript by Language Editor	2014-07-20 11:09
Typeset the Manuscript	2014-12-13 14:23
Publish the Manuscript Online	2015-01-06 09:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Evidence-Based Medicine
Article Title	T helper cell dysregulation with hepatitis B and rebalance with glucocorticoids
Manuscript Source	Unsolicited Manuscript
All Author List	Zhong-Hua Lu, Xiao-Ping Huang, Wei Sun, Yi-Ling Zhu, Juan-Juan Cui, Wei Chen, Li-Hua Huang, Shou-Gang Kuai, He-Juan Du, Zhao-Xia Ju and Jian-He Gan
Funding Agency and Grant Number
Corresponding Author	Jian-He Gan, Professor, Chief, Department of Infectious Disease, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215006, Jiangsu Province, China. ganjianhe@aliyun.com
Key Words	Severe hepatitis B; T helper 17 cell; Regulatory T cell; Dysregulation; Glucocorticoid
Core Tip	Severe hepatitis B (SHB) is a fast progressing form of hepatitis infection with a low eradication rate. Patients with SHB have dysregulated ratios of T helper cells, observed as elevated levels of T helper 17 cells and reduced regulatory T cells. This study demonstrates that these levels can be rebalanced with glucocorticoid treatment. However, failure to rectify the imbalance likely will results in the progression of SHB and eventually cause death.
Publish Date	2015-01-06 09:08
Citation	Lu ZH, Huang XP, Sun W, Zhu YL, Cui JJ, Chen W, Huang LH, Kuai SG, Du HJ, Ju ZX, Gan JH. T helper cell dysregulation with hepatitis B and rebalance with glucocorticoids. World J Gastroenterol 2014; 20(48): 18354-18359
URL	http://www.wjgnet.com/1007-9327/full/v20/i48/18354.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i48.18354

Full Article (PDF)	WJG-20-18354.pdf
Full Article (Word)	WJG-20-18354.doc
Manuscript File	10811-Review.doc
Answering Reviewers	10811-Answering reviewers.pdf
Copyright License Agreement	10811-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	10811-Language certificate.pdf
Peer-review Report	10811-Peer review.pdf
Scientific Misconduct Check	10811-CrossCheck.jpg
Scientific Editor Work List	10811-Scientific editor work list.pdf