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8/20/2025 8:41:20 AM | Browse: 7 | Download: 0
Publication Name World Journal of Clinical Oncology
Manuscript ID 108112
Country Bosnia and Herzegovina
Received
2025-04-08 15:20
Peer-Review Started
2025-04-08 15:20
To Make the First Decision
Return for Revision
2025-04-17 11:01
Revised
2025-04-25 22:42
Second Decision
2025-06-25 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-25 07:00
Articles in Press
2025-06-25 07:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-07 02:40
Publish the Manuscript Online
2025-08-20 08:41
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neurosciences
Manuscript Type Minireviews
Article Title Glucose and antidiabetic therapy in temozolomide resistance in glioblastoma
Manuscript Source Invited Manuscript
All Author List Emir Begagić, Amina Džidić-Krivić, Hakija Bečulić, Ragib Pugonja, Adnana Ljevaković, Binasa Bašić, Adem Nuhović, Elma Milanović, Semir Hadžić, Emir Bećirović, Lemana Buljubašić, Minela Bećirović and Mirza Pojskić
ORCID
Author(s) ORCID Number
Emir Begagić http://orcid.org/0000-0002-3988-8911
Funding Agency and Grant Number
Corresponding Author Emir Begagić, Academic Editor, MD, Department of Neurosurgery, Cantonal Hospital Zenica, Crkvice 67, Zenica 72000, Bosnia and Herzegovina. begagicem@gmail.com
Key Words Drug resistance; Glioblastoma multiforme; Neoplasms; Glucose metabolism; Antidiabetic drugs
Core Tip Metformin shows promise as an adjunct therapy in glioblastoma by modulating glucose metabolism, enhancing temozolomide efficacy, and targeting glioma stem cells. Its ability to cross the blood-brain barrier and influence pathways such as AMPK and Wnt highlights its potential. However, its impact on survival remains unclear, requiring further clinical validation.
Publish Date 2025-08-20 08:41
Citation <p>Begagić E, Džidić-Krivić A, Bečulić H, Pugonja R, Ljevaković A, Bašić B, Nuhović A, Milanović E, Hadžić S, Bećirović E, Buljubašić L, Bećirović M, Pojskić M. Glucose and antidiabetic therapy in temozolomide resistance in glioblastoma. <i>World J Clin Oncol</i> 2025; 16(8): 108112</p>
URL https://www.wjgnet.com/2218-4333/full/v16/i8/108112.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i8.108112
Full Article (PDF) WJCO-16-108112-with-cover.pdf
Manuscript File 108112_Auto_Edited_023354.docx
Answering Reviewers 108112-answering-reviewers.pdf
Audio Core Tip 108112-audio.mp3
Conflict-of-Interest Disclosure Form 108112-conflict-of-interest-statement.pdf
Copyright License Agreement 108112-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 108112-non-native-speakers.pdf
Supplementary Material 108112-supplementary-material.pdf
Peer-review Report 108112-peer-reviews.pdf
Scientific Misconduct Check 108112-scientific-misconduct-check.png
Scientific Editor Work List 108112-scientific-editor-work-list.pdf
CrossCheck Report 108112-crosscheck-report.pdf