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8/5/2025 8:58:37 AM | Browse: 43 | Download: 100
Publication Name World Journal of Clinical Cases
Manuscript ID 108117
Country China
Received
2025-04-07 11:15
Peer-Review Started
2025-04-07 11:15
To Make the First Decision
Return for Revision
2025-05-12 02:10
Revised
2025-05-17 02:16
Second Decision
2025-06-16 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-17 00:58
Articles in Press
2025-06-17 00:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-06-18 13:55
Typeset the Manuscript
2025-07-21 06:06
Publish the Manuscript Online
2025-08-05 08:58
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Dentistry, Oral Surgery & Medicine
Manuscript Type Letter to the Editor
Article Title Unraveling the enigma of salivary uric acid in periodontitis: Independent association, mechanistic insights, and future trajectories
Manuscript Source Invited Manuscript
All Author List Dan-Dan Shi, Jing Ding and Ju Tian
ORCID
Author(s) ORCID Number
Ju Tian http://orcid.org/0000-0003-2494-2679
Funding Agency and Grant Number
Corresponding Author Ju Tian, Department of Burns and Plastic Surgery, Zhongshan City People’s Hospital, Sunwen East Road, Zhongshan 528400, Guangdong Province, China. tian-ju@163.com
Key Words Diagnostic biomarkers; Mechanistic hypotheses; Oxidative stress; Periodontitis; Salivary uric acid
Core Tip This article delves into salivary uric acid's (UA) dual role in periodontitis—antioxidant under normal conditions, pro-inflammatory under pathology. Studies show an inverse link between UA levels and periodontitis severity, with 111 nmol/mL as a diagnostic marker. Future research should prioritize longitudinal validation, multi-omics analysis, and therapeutic strategies.
Publish Date 2025-08-05 08:58
Citation <p>Shi DD, Ding J, Tian J. Unraveling the enigma of salivary uric acid in periodontitis: Independent association, mechanistic insights, and future trajectories. <i>World J Clin Cases</i> 2025; 13(27): 108117</p>
URL https://www.wjgnet.com/2307-8960/full/v13/i27/108117.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i27.108117
Full Article (PDF) WJCC-13-108117-with-cover.pdf
Manuscript File 108117_Auto_Edited_071737.docx
Answering Reviewers 108117-answering-reviewers.pdf
Audio Core Tip 108117-audio.mp3
Conflict-of-Interest Disclosure Form 108117-conflict-of-interest-statement.pdf
Copyright License Agreement 108117-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 108117-non-native-speakers.pdf
Peer-review Report 108117-peer-reviews.pdf
Scientific Misconduct Check 108117-scientific-misconduct-check.png
Scientific Editor Work List 108117-scientific-editor-work-list.pdf
CrossCheck Report 108117-crosscheck-report.pdf