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Articles Published Processes
9/25/2025 11:24:01 AM | Browse: 65 | Download: 20
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Received |
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2025-04-08 14:03 |
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Peer-Review Started |
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2025-04-17 09:06 |
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To Make the First Decision |
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Return for Revision |
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2025-05-17 08:36 |
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2025-06-13 08:00 |
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Second Decision |
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2025-08-04 02:52 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-04 10:11 |
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Articles in Press |
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2025-08-04 10:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-17 03:08 |
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Publish the Manuscript Online |
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2025-09-25 11:24 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Research & Experimental Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
Impact of metabolic endoscopy on fibrosis regression in steatotic liver disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Leandro Sierra, Arjun Chatterjee, Renan Prado, Akash Khurana, Roma Patel, Stephen Firkins and Roberto Simons-Linares |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Roberto Simons-Linares, MD, Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, United States. simonsc@ccf.org |
| Key Words |
Steatotic liver disease; Metabolic dysfunction associated steatohepatitis; Endoscopic bariatric metabolic therapies; Liver fibrosis regression; Endoscopic sleeve gastroplasty; Revisional metabolic endoscopy procedures |
| Core Tip |
This review highlights the promise of metabolic endoscopy as a minimally invasive strategy for reversing liver fibrosis in patients with metabolic dysfunction-associated steatohepatitis. It evaluates endoscopic bariatric metabolic therapies including endoscopic sleeve gastroplasty (ESG), intragastric balloon, duodenal mucosal resurfacing (DMR), and duodeno-jejunal bypass liners, along with revisional procedures such as endoscopic revisional gastroplasty (ERG) and transoral outlet reduction (TORe). Evidence indicates that ESG yields the greatest fibrosis reduction, while DMR shows minimal benefit and is not recommended. Among revisional metabolic endoscopic procedures, ERG is effective for fibrosis reduction, whereas TORe requires further evaluation. |
| Publish Date |
2025-09-25 11:24 |
| Citation |
<p>Sierra L, Chatterjee A, Prado R, Khurana A, Patel R, Firkins S, Simons-Linares R. Impact of metabolic endoscopy on fibrosis regression in steatotic liver disease. <i>World J Hepatol</i> 2025; 17(9): 108144</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i9/108144.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i9.108144 |
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