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Articles Published Processes
7/14/2025 12:55:52 PM | Browse: 4 | Download: 13
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Received |
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2025-04-15 09:37 |
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Peer-Review Started |
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2025-04-15 09:37 |
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To Make the First Decision |
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Return for Revision |
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2025-04-30 07:17 |
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Revised |
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2025-05-12 07:42 |
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Second Decision |
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2025-05-29 02:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-29 06:38 |
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Articles in Press |
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2025-05-29 06:38 |
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Publication Fee Transferred |
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2025-05-17 01:30 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-29 12:23 |
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Publish the Manuscript Online |
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2025-07-14 12:55 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Effects of radiotherapy on lymphocytes in patients with middle and lower esophageal cancer and its relationship with prognosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shu-Guang Li, Yang Liu, Xue-Yuan Zhang, You-Mei Li, Wen-Bin Shen and Shu-Chai Zhu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Shu-Chai Zhu, Chief Physician, Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, No. 12 Jiankang Road, Shijiazhuang 050011, Hebei Province, China. hbmuzhusc1965@hebmu.edu.cn |
| Key Words |
Esophageal tumor; Radiotherapy; Radiation-induced lymphopenia; Prognosis; Organs at risk volume; Immunosuppression |
| Core Tip |
Definitive chemoradiotherapy is the standard treatment for locally advanced esophageal cancer. However, radiotherapy (RT) often affects the immune system of patients. One of the possible mechanisms of lymphopenia after RT is that a large number of circulating lymphocytes in the systemic and pulmonary circulation will be killed by more sessions of low-dose radiation. This study showed that there was a relationship between radiation-induced lymphopenia (RIL) and the prognosis of esophageal squamous cell carcinoma patients, and identified several possible mechanisms of RT parameters in regulating the lymphocyte count during RT. The combination of tumor clinical stage and RT parameters has a certain predictive value for RIL and patient prognosis. |
| Publish Date |
2025-07-14 12:55 |
| Citation |
<p>Li SG, Liu Y, Zhang XY, Li YM, Shen WB, Zhu SC. Effects of radiotherapy on lymphocytes in patients with middle and lower esophageal cancer and its relationship with prognosis. <i>World J Gastrointest Oncol</i> 2025; 17(7): 108205</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i7/108205.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i7.108205 |
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