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Articles Published Processes
8/26/2025 10:18:31 AM | Browse: 142 | Download: 182
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Received |
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2025-04-08 13:54 |
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Peer-Review Started |
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2025-04-09 02:40 |
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First Decision by Editorial Office Director |
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2025-04-30 07:32 |
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Return for Revision |
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2025-04-30 07:32 |
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Revised |
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2025-05-13 20:13 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-07-23 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-23 07:23 |
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Articles in Press |
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2025-07-23 07:23 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-14 09:19 |
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Publish the Manuscript Online |
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2025-08-26 10:18 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Unmet needs in precision psychiatry
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Philipp G Sand, Timm B Poeppl and Vera Roessler |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Philipp G Sand, Associate Professor, MD, Department of Psychiatry, University of Regensburg, Universitätsstr. 84, Regensburg 93053, Bavaria, Germany. philipp.sand@ukr.de |
| Key Words |
C-1019G polymorphism; 5-HTR1A gene; Meta-analysis; Antidepressant efficacy; Major depressive disorder |
| Core Tip |
A recent meta-analysis has suggested a 5-HTR1A promoter variant may predict antidepressant response. However, re-analysis of the original data unveiled numerous shortcomings pertaining to genetic exposure and interpretation of genetic findings. We alert to ambiguities that are likely to have introduced bias in the calculation of overall effects by muddling of alleles or entire genes, and by demographic inaccuracies. In part, these may be explained by specific features of genetic information that are not encoded in the DNA sequence, such as transcriptional orientation. |
| Publish Date |
2025-08-26 10:18 |
| Citation |
Sand PG, Poeppl TB, Roessler V. Unmet needs in precision psychiatry. World J Psychiatry 2025; 15(9): 108222 |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i9/108222.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i9.108222 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
