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9/25/2025 11:24:01 AM | Browse: 57 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 108259
Country Thailand
Received
2025-04-09 02:00
Peer-Review Started
2025-04-09 02:00
To Make the First Decision
Return for Revision
2025-05-07 18:31
Revised
2025-05-18 15:52
Second Decision
2025-08-12 02:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-13 00:34
Articles in Press
2025-08-13 00:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-12 03:11
Publish the Manuscript Online
2025-09-25 11:24
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Extracellular vesicles in metabolic dysfunction-associated steatotic liver disease: From intercellular signaling to clinical translation
Manuscript Source Invited Manuscript
All Author List Bootsakorn Boonkaew, Denita Charoenthanakitkul, Nuchanart Suntornnont, Chaiyaboot Ariyachet and Pisit Tangkijvanich
ORCID
Author(s) ORCID Number
Bootsakorn Boonkaew http://orcid.org/0000-0002-9548-1059
Chaiyaboot Ariyachet http://orcid.org/0000-0001-8647-7376
Pisit Tangkijvanich http://orcid.org/0000-0002-2926-8671
Funding Agency and Grant Number
Corresponding Author Chaiyaboot Ariyachet, Assistant Professor, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, 1873 Paettayaphat Bldg, Rama IV Rd, Bangkok 10330, Thailand. chaiyaboot.a@chula.ac.th
Key Words Metabolic dysfunction-associated steatotic liver disease; Metabolic dysfunction-associated steatohepatitis; Extracellular vesicles; Fibrosis; Lipotoxicity
Core Tip Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health concern that progresses from simple steatosis to cirrhosis. Extracellular vesicles (EVs) have emerged as key mediators of MASLD pathogenesis, influencing lipotoxicity, inflammation, and fibrosis through bioactive cargoes such as microRNAs. This review highlights the role of EVs in MASLD progression, their diagnostic and prognostic potential, and EV-based therapeutic strategies. We also address current challenges, emerging research trends, and future perspectives, emphasizing the translational potential of EVs for improving patient outcomes.
Publish Date 2025-09-25 11:24
Citation <p>Boonkaew B, Charoenthanakitkul D, Suntornnont N, Ariyachet C, Tangkijvanich P. Extracellular vesicles in metabolic dysfunction-associated steatotic liver disease: From intercellular signaling to clinical translation. <i>World J Hepatol</i> 2025; 17(9): 108259</p>
URL https://www.wjgnet.com/1948-5182/full/v17/i9/108259.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i9.108259
Full Article (PDF) WJH-17-108259-with-cover.pdf
Manuscript File 108259_Auto_Edited_012920.docx
Answering Reviewers 108259-answering-reviewers.pdf
Audio Core Tip 108259-audio.m4a
Conflict-of-Interest Disclosure Form 108259-conflict-of-interest-statement.pdf
Copyright License Agreement 108259-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 108259-non-native-speakers.pdf
Peer-review Report 108259-peer-reviews.pdf
Scientific Misconduct Check 108259-scientific-misconduct-check.png
Scientific Editor Work List 108259-scientific-editor-work-list.pdf
CrossCheck Report 108259-crosscheck-report.pdf