Publication Name	World Journal of Gastroenterology
Manuscript ID	108271
Country	Mexico

Received	2025-04-09 10:11
Peer-Review Started	2025-04-09 10:12
To Make the First Decision
Return for Revision	2025-05-10 19:00
Revised	2025-05-24 02:32
Second Decision	2025-07-04 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-04 07:21
Articles in Press	2025-07-04 07:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-07-14 00:56
Publish the Manuscript Online	2025-07-24 07:47

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Phospholipase D2: A biomarker implicated in various pancreatic diseases beyond acute pancreatitis
Manuscript Source	Invited Manuscript
All Author List	Ana I Tornel Avelar, Christian Navarro Gerrard and Bryan Adrian Priego Parra
ORCID	Author(s) ORCID Number Ana I Tornel Avelar http://orcid.org/0000-0003-0865-0596 Christian Navarro Gerrard http://orcid.org/0000-0002-8367-6916 Bryan Adrian Priego Parra http://orcid.org/0000-0003-1506-806X
Funding Agency and Grant Number	Funding Agency Grant Number Mexican Association of Gastroenterology 2023 for the scholarship warded
Corresponding Author	Bryan Adrian Priego Parra, MD, PhD, Department of Digestive Physiology and Gastrointestinal Motility, Institute of Medical-Biological Research, Universidad Veracruzana, Iturbide S/N Entre Carmen Serdán y 20 de Noviembre, Col. Flores Magón, Veracruz 91700, Veracruz, Mexico. bryanpriegop@gmail.com
Key Words	Phospholipase D2; Acute pancreatitis; Chronic pancreatitis; Pancreatic Biomarkers; Pancreatic cancer; Sexual dimorphism
Core Tip	Phospholipase D2 is a key enzyme involved in the hydrolysis of phospholipids. It has been implicated in processes, such as neutrophil migration, the inflammatory response, apoptosis, cell migration, and adhesion in various pathologies. This letter to the editor analyzes multiple research sources on phospholipase D2 in pancreatic conditions, including acute pancreatitis, chronic pancreatitis, and pancreatic cancer. It also highlights the need for future research to consider sex differences in the expression of this enzyme and to evaluate its applicability in clinical practice.
Publish Date	2025-07-24 07:47
Citation	<p>Tornel Avelar AI, Gerrard CN, Priego Parra BA. Phospholipase D2: A biomarker implicated in various pancreatic diseases beyond acute pancreatitis. <i>World J Gastroenterol</i> 2025; 31(28): 108271</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i28/108271.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i28.108271

Full Article (PDF)	WJG-31-108271-with-cover.pdf
Manuscript File	108271_Auto_Edited_071914.docx
Answering Reviewers	108271-answering-reviewers.pdf
Audio Core Tip	108271-audio.mp4
Conflict-of-Interest Disclosure Form	108271-conflict-of-interest-statement.pdf
Copyright License Agreement	108271-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	108271-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	108271-non-native-speakers.pdf
Peer-review Report	108271-peer-reviews.pdf
Scientific Misconduct Check	108271-scientific-misconduct-check.png
Scientific Editor Work List	108271-scientific-editor-work-list.pdf
CrossCheck Report	108271-crosscheck-report.pdf