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Articles Published Processes
11/28/2025 2:00:41 PM | Browse: 32 | Download: 86
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Received |
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2025-04-14 04:30 |
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Peer-Review Started |
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2025-04-14 04:30 |
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First Decision by Editorial Office Director |
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2025-05-12 03:03 |
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Return for Revision |
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2025-05-12 03:03 |
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Revised |
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2025-05-23 10:13 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-08-05 02:48 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-05 11:38 |
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Articles in Press |
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2025-08-05 11:38 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-17 04:03 |
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Publish the Manuscript Online |
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2025-11-28 14:00 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
Haemostasis and beyond: The expanding role of desmopressin in intensive care
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Saketh Vinjamuri, Ekta Tiwari, Sahil Kataria and Deven Juneja |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Deven Juneja, Director, MD, Institute of Critical Care Medicine, Max Super Speciality Hospital, Saket, 1 Press Enclave Road, New Delhi 110017, India. devenjuneja@gmail.com |
| Key Words |
Antidiuretic hormone; Critical care; Desmopressin; Intensive care unit; Platelet dysfunction |
| Core Tip |
In recent years, desmopressin has emerged as a potentially valuable agent in managing complex scenarios such as uremic platelet dysfunction, trauma-associated coagulopathy, intracranial hemorrhage, von Willebrand disease, and central diabetes insipidus. These conditions may be particularly challenging to manage, especially in critically ill patients. Emerging evidence suggests that desmopressin use may improve surrogate outcomes such as bleeding time and transfusion reduction. However, its impact on long-term clinical outcomes remains under investigation. The primary safety concern is hyponatremia due to water retention, which necessitates proactive fluid restriction and electrolyte monitoring. Thrombotic risk is low but warrants caution in high-risk patients. Despite its increasing application in intensive care units, desmopressin use remains largely empirical in many of these off-label contexts. This is because there is no universally accepted guidance on optimal dosing strategies, timing of administration, or patient selection. |
| Publish Date |
2025-11-28 14:00 |
| Citation |
Vinjamuri S, Tiwari E, Kataria S, Juneja D. Haemostasis and beyond: The expanding role of desmopressin in intensive care. World J Crit Care Med 2025; 14(4): 108370 |
| URL |
https://www.wjgnet.com/2220-3141/full/v14/i4/108370.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v14.i4.108370 |
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