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Articles Published Processes
10/16/2025 9:32:19 AM | Browse: 13 | Download: 45
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Received |
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2025-04-14 03:40 |
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Peer-Review Started |
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2025-04-14 03:40 |
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To Make the First Decision |
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Return for Revision |
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2025-05-20 09:29 |
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Revised |
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2025-05-28 19:14 |
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Second Decision |
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2025-09-09 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-10 08:42 |
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Articles in Press |
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2025-09-10 08:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-10 00:49 |
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Publish the Manuscript Online |
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2025-10-16 09:32 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Metagenomic analysis of gut microbiome and spondyloarthropathy: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Madhan Jeyaraman, Easwar Balasubramanian, Naveen Jeyaraman, Arulkumar Nallakumarasamy and Sathish Muthu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Madhan Jeyaraman, Assistant Professor, MD, PhD, Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Velappanchavadi, Chennai 600077, Tamil Nadu, India. madhanjeyaraman@gmail.com |
| Key Words |
Spondyloarthritis; Ankylosing arthritis; Gut microbiome; Metagenomic sequencing |
| Core Tip |
Spondyloarthritis (SpA) is a chronic inflammatory condition impacting the axial skeleton, with emerging links to gut microbiome dysbiosis. A systematic review highlights enrichment of pathogenic bacterial and viral species in SpA patients, suggesting gut microbes contribute to disease progression. Dysregulated metabolic pathways may mediate inflammation, while tumor necrosis factor inhibitors show promise in symptom relief and microbial balance restoration. Targeting specific microbial species may unlock innovative therapies for SpA management and gut dysbiosis prevention. |
| Publish Date |
2025-10-16 09:32 |
| Citation |
<p>Jeyaraman M, Balasubramanian E, Jeyaraman N, Nallakumarasamy A, Muthu S. Metagenomic analysis of gut microbiome and spondyloarthropathy: A systematic review. <i>World J Orthop</i> 2025; 16(10): 108374</p> |
| URL |
https://www.wjgnet.com/2218-5836/full/v16/i10/108374.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v16.i10.108374 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
