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Articles Published Processes
8/25/2025 12:36:18 PM | Browse: 96 | Download: 154
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Received |
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2025-04-14 09:17 |
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Peer-Review Started |
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2025-04-14 09:17 |
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To Make the First Decision |
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Return for Revision |
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2025-05-09 05:23 |
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Revised |
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2025-05-20 03:16 |
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Second Decision |
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2025-06-16 02:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-16 10:09 |
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Articles in Press |
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2025-06-16 10:09 |
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Publication Fee Transferred |
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2025-05-24 10:38 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-07 08:45 |
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Publish the Manuscript Online |
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2025-08-25 12:36 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Differential effects of the KRAS gene on recurrence in right- vs left-sided colorectal liver metastases undergoing radiofrequency ablation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bin-Bin Jiang, Ji-Chen Wang, Kun Yan, Zhong-Yi Zhang, Song Wang, Wei Wu and Wei Yang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82472002 |
| Capital Health Development Research Project |
2020-2-2152 |
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| Corresponding Author |
Kun Yan, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. ydbz@vip.sina.com |
| Key Words |
Recurrence; Primary tumor location; Radiofrequency ablation; Colorectal cancer |
| Core Tip |
The mutation status of the KRAS differentially impacts intrahepatic recurrence after radiofrequency ablation (RFA) for colorectal liver metastases (CLMs) based on primary tumor location. Patients with left-sided colorectal cancer harboring KRAS mutations have significantly worse intrahepatic recurrence-free survival post-RFA, whereas no such association exists in right-sided patients. KRAS status was not correlated with extrahepatic recurrence, regardless of tumor origin. These findings highlight the clinical value of incorporating both primary tumor location and KRAS genotyping to optimize post-RFA management strategies, enabling personalized approaches to reduce recurrence risk and improve long-term outcomes in CLM patients. |
| Publish Date |
2025-08-25 12:36 |
| Citation |
<p>Jiang BB, Wang JC, Yan K, Zhang ZY, Wang S, Wu W, Yang W. Differential effects of the KRAS gene on recurrence in right- vs left-sided colorectal liver metastases undergoing radiofrequency ablation. <i>World J Gastrointest Surg</i> 2025; 17(8): 108418</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i8/108418.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i8.108418 |
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