BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
7/24/2025 9:11:32 AM | Browse: 8 | Download: 26
Publication Name World Journal of Stem Cells
Manuscript ID 108519
Country United States
Received
2025-04-16 06:40
Peer-Review Started
2025-04-16 06:40
To Make the First Decision
Return for Revision
2025-05-15 12:34
Revised
2025-05-27 07:12
Second Decision
2025-06-13 10:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-16 10:21
Articles in Press
2025-06-16 10:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-06-21 20:02
Typeset the Manuscript
2025-07-15 14:51
Publish the Manuscript Online
2025-07-24 09:11
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Dermatology
Manuscript Type Systematic Reviews
Article Title Therapeutic potential of stem cells-derived exosomes in hair regeneration: A systematic review
Manuscript Source Invited Manuscript
All Author List Neil Poddar, Adarsh Aratikatla and Ashim Gupta
ORCID
Author(s) ORCID Number
Ashim Gupta http://orcid.org/0000-0003-1224-2755
Funding Agency and Grant Number
Corresponding Author Ashim Gupta, PhD, President, Professor, Department of Orthopaedics and Regenerative Medicine, Future Biologics, 2505 Newpoint Pkwy, Lawrenceville, GA 30043, United States. ashim6786@gmail.com
Key Words Regenerative medicine; Secretome; Extracellular vesicles; Exosomes; Stem cells; Hair regeneration; Hair loss; Alopecia
Core Tip This review synthesizes findings from in vitro, preclinical, and clinical studies to evaluate the efficacy, mechanisms, and challenges associated with exosome-based hair restoration therapies. Twenty seven studies met our pre-defined search and inclusion criteria and were included in this review. Exosome-based therapies hold immense promise for hair regeneration by leveraging their ability to modulate key signaling pathways and enhance hair follicle regeneration. While in vitro and preclinical studies demonstrate consistent efficacy across diverse exosome sources, methodological heterogeneity and limited number of clinical studies warrant further clinical research to realize their full clinical potential for hair regeneration.
Publish Date 2025-07-24 09:11
Citation <p>Poddar N, Aratikatla A, Gupta A. Therapeutic potential of stem cells-derived exosomes in hair regeneration: A systematic review. <i>World J Stem Cells</i> 2025; 17(7): 108519</p>
URL https://www.wjgnet.com/1948-0210/full/v17/i7/108519.htm
DOI https://dx.doi.org/10.4252/wjsc.v17.i7.108519
Full Article (PDF) WJSC-17-108519-with-cover.pdf
PRISMA 2009 Checklist 108519-PRISMA-2009-Checklist.pdf
Manuscript File 108519_Auto_Edited_074618.docx
Answering Reviewers 108519-answering-reviewers.pdf
Audio Core Tip 108519-audio.mp4
Biostatistics Review Certificate 108519-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 108519-conflict-of-interest-statement.pdf
Copyright License Agreement 108519-copyright-assignment.pdf
Peer-review Report 108519-peer-reviews.pdf
Scientific Misconduct Check 108519-scientific-misconduct-check.png
Scientific Editor Work List 108519-scientific-editor-work-list.pdf
CrossCheck Report 108519-crosscheck-report.pdf