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Articles Published Processes
7/24/2025 9:11:32 AM | Browse: 8 | Download: 26
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Received |
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2025-04-16 06:40 |
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Peer-Review Started |
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2025-04-16 06:40 |
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To Make the First Decision |
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Return for Revision |
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2025-05-15 12:34 |
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Revised |
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2025-05-27 07:12 |
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Second Decision |
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2025-06-13 10:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-16 10:21 |
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Articles in Press |
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2025-06-16 10:21 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-06-21 20:02 |
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Typeset the Manuscript |
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2025-07-15 14:51 |
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Publish the Manuscript Online |
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2025-07-24 09:11 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Dermatology |
Manuscript Type |
Systematic Reviews |
Article Title |
Therapeutic potential of stem cells-derived exosomes in hair regeneration: A systematic review
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Manuscript Source |
Invited Manuscript |
All Author List |
Neil Poddar, Adarsh Aratikatla and Ashim Gupta |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Ashim Gupta, PhD, President, Professor, Department of Orthopaedics and Regenerative Medicine, Future Biologics, 2505 Newpoint Pkwy, Lawrenceville, GA 30043, United States. ashim6786@gmail.com |
Key Words |
Regenerative medicine; Secretome; Extracellular vesicles; Exosomes; Stem cells; Hair regeneration; Hair loss; Alopecia |
Core Tip |
This review synthesizes findings from in vitro, preclinical, and clinical studies to evaluate the efficacy, mechanisms, and challenges associated with exosome-based hair restoration therapies. Twenty seven studies met our pre-defined search and inclusion criteria and were included in this review. Exosome-based therapies hold immense promise for hair regeneration by leveraging their ability to modulate key signaling pathways and enhance hair follicle regeneration. While in vitro and preclinical studies demonstrate consistent efficacy across diverse exosome sources, methodological heterogeneity and limited number of clinical studies warrant further clinical research to realize their full clinical potential for hair regeneration. |
Publish Date |
2025-07-24 09:11 |
Citation |
<p>Poddar N, Aratikatla A, Gupta A. Therapeutic potential of stem cells-derived exosomes in hair regeneration: A systematic review. <i>World J Stem Cells</i> 2025; 17(7): 108519</p> |
URL |
https://www.wjgnet.com/1948-0210/full/v17/i7/108519.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v17.i7.108519 |
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