Publication Name	World Journal of Gastroenterology
Manuscript ID	10852
Country	Japan

Received	2014-04-23 08:52
Peer-Review Started	2014-04-23 16:59
First Decision by Editorial Office Director
Return for Revision	2014-06-04 20:46
Revised	2014-06-09 06:22
Publication Fee Transferred
Second Decision by Editor	2014-07-16 17:22
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-07-16 17:34
Articles in Press	2014-07-16 17:53
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-17 15:43
Publish the Manuscript Online	2015-01-06 09:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Prospective Study
Article Title	Treatment outcomes of chemotherapy between unresectable and recurrent biliary tract cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Takashi Sasaki, Hiroyuki Isayama, Yousuke Nakai, Yukiko Ito, Ichiro Yasuda, Nobuo Toda, Hiroshi Yagioka, Saburo Matsubara, Keiji Hanada, Hiroyuki Maguchi, Hideki Kamada, Osamu Hasebe, Tsuyoshi Mukai, Yoshihiro Okabe, Iruru Maetani and Kazuhiko Koike
Funding Agency and Grant Number
Corresponding Author	Hiroyuki Isayama MD, PhD, Department of Gastroenterology, Graduate School of Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. isayama-2im@h.u-tokyo.ac.jp
Key Words	Biliary tract cancer; Unresectable; Recurrent; Pooled analysis; Chemotherapy
Core Tip	Many chemotherapeutic studies of advanced biliary tract cancer include both unresectable and recurrent cases. However, the treatment outcomes of these two conditions might be different. We therefore conducted a pooled analysis of two prospective studies to evaluate the differences in the treatment outcomes between the unresectable and recurrent cases in patients with advanced biliary tract cancer patients who received chemotherapy. From our pooled analysis, not only the efficacy but also the toxicity and dose intensity were significantly different between these two conditions. Therefore, it is better to evaluate the unresectable and recurrent cases separately in future prospective studies.
Publish Date	2015-01-06 09:08
Citation	Sasaki T, Isayama H, Nakai Y, Ito Y, Yasuda I, Toda N, Yagioka H, Matsubara S, Hanada K, Maguchi H, Kamada H, Hasebe O, Mukai T, Okabe Y, Maetani I, Koike K. Treatment outcomes of chemotherapy between unresectable and recurrent biliary tract cancer. World J Gastroenterol 2014; 20(48): 18452-18457
URL	http://www.wjgnet.com/1007-9327/full/v20/i48/18452.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i48.18452

Full Article (PDF)	WJG-20-18452.pdf
Full Article (Word)	WJG-20-18452.doc
Manuscript File	10852-Review.doc
Answering Reviewers	10852-Answering reviewers.pdf
Copyright License Agreement	10852-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	10852-Language certificate.pdf
Peer-review Report	10852-Peer revew.pdf
Scientific Misconduct Check	10852-CorssCheck.jpg