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Articles Published Processes
10/31/2025 3:02:53 PM | Browse: 12 | Download: 58
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Received |
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2025-04-17 11:29 |
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Peer-Review Started |
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2025-04-17 11:29 |
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First Decision by Editorial Office Director |
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2025-05-01 02:18 |
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Return for Revision |
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2025-05-01 02:18 |
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Revised |
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2025-05-14 16:21 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-08-12 02:58 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-13 00:58 |
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Articles in Press |
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2025-08-13 00:58 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-20 02:46 |
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Publish the Manuscript Online |
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2025-10-31 15:02 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Minireviews |
| Article Title |
Research on gamma globulin unresponsive Kawasaki disease: A review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zu-Chuang Wu and Yan Pan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yan Pan, Researcher, Department of Pediatrics, The First Affiliated Hospital of Yangtze University, No. 55 Jianghan North Road, Shashi District, Jingzhou 434000, Hubei Province, China. woshipanyan@126.com |
| Key Words |
Kawasaki disease; Intravenous immunoglobulin resistance; Biomarkers; Immunomodulation; Coronary artery lesions |
| Core Tip |
Gamma globulin-unresponsive Kawasaki disease (KD) poses significant clinical challenges due to its complex pathophysiology and variable treatment outcomes. This review synthesizes current knowledge on epidemiology, IVIG resistance mechanisms, diagnostic criteria, and evolving therapeutic strategies (e.g., corticosteroids, biologics). Key controversies include optimal second-line therapies and long-term cardiovascular monitoring. Future directions emphasize targeted drug development and international collaboration to improve management of refractory KD. |
| Publish Date |
2025-10-31 15:02 |
| Citation |
Wu ZC, Pan Y. Research on gamma globulin unresponsive Kawasaki disease: A review. World J Clin Pediatr 2025; 14(4): 108520 |
| URL |
https://www.wjgnet.com/2219-2808/full/v14/i4/108520.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v14.i4.108520 |
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