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Articles Published Processes
9/24/2025 3:48:36 AM | Browse: 40 | Download: 111
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Received |
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2025-04-17 03:26 |
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Peer-Review Started |
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2025-04-17 03:26 |
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First Decision by Editorial Office Director |
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2025-05-13 12:26 |
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Return for Revision |
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2025-05-13 12:26 |
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Revised |
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2025-05-27 11:30 |
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Publication Fee Transferred |
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2025-05-28 12:16 |
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Second Decision by Editor |
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2025-07-07 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-08 06:55 |
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Articles in Press |
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2025-07-08 06:55 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-11 10:05 |
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Publish the Manuscript Online |
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2025-09-24 03:48 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell & Tissue Engineering |
| Manuscript Type |
Review |
| Article Title |
Stem cell-based cartilage regeneration: Biological strategies, engineering innovations, and clinical translation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bo Cong, Feng-Hua Zhang and Hai-Guang Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Yantai Science and Technology Innovation Development Plan Project |
2023YD048 |
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| Corresponding Author |
Hai-Guang Zhang, Department of Orthopaedics, Yantaishan Hospital, Yantaishan Hospital Affiliated to Binzhou Medical University, Yantai Key Laboratory for Repair and Reconstruction of Bone & Joint, No. 10087 Science and Technology Avenue, Laishan District, Yantai 264003, Shandong Province, China. zhg10087@163.com |
| Key Words |
Gene editing; Osteoarthritis; Three-dimensional bioprinting; Tissue engineering; Induced pluripotent stem cells; Mesenchymal stem cells; Cartilage regeneration |
| Core Tip |
This review highlights the emerging role of stem cell-based strategies in articular cartilage regeneration. By integrating the biological potential of mesenchymal stem cells and induced pluripotent stem cells with engineering advances such as bioactive scaffolds, growth factor delivery, and three-dimensional bioprinting, these approaches aim to overcome the limitations of traditional therapies. We also discuss cutting-edge developments including gene editing and exosome-based therapeutics, offering new insights into personalized and durable cartilage repair solutions. |
| Publish Date |
2025-09-24 03:48 |
| Citation |
Cong B, Zhang FH, Zhang HG. Stem cell-based cartilage regeneration: Biological strategies, engineering innovations, and clinical translation. World J Stem Cells 2025; 17(9): 108523 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i9/108523.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i9.108523 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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