Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	108600
Country	Taiwan

Received	2025-04-18 03:01
Peer-Review Started	2025-04-18 03:01
To Make the First Decision
Return for Revision	2025-05-09 05:22
Revised	2025-05-22 03:40
Second Decision	2025-06-23 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-23 06:56
Articles in Press	2025-06-23 06:56
Publication Fee Transferred	2025-05-23 20:48
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-08-07 08:52
Publish the Manuscript Online	2025-08-25 12:36

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Observational Study
Article Title	Morphomics in esophageal cancer: Validation and association with muscular and cardiorespiratory fitness
Manuscript Source	Unsolicited Manuscript
All Author List	Watson Hua-Sheng Tseng, Shu-Chun Huang, Stewart C Wang, Jules Lin, Peng Zhang, Yu-Chen Liu, Yin-Kai Chao and Chien-Hung Chiu
ORCID	Author(s) ORCID Number Chien-Hung Chiu http://orcid.org/0000-0002-3643-1596
Funding Agency and Grant Number	Funding Agency Grant Number Chang Gung Memorial Hospital CMRPG3N1171 and CMRPG3N1172 Chang Gung Memorial Hospital CORPVVN0071, CMRPVVK0111-3 and CMRPVVL0121-3 National Science and Technology Council, Taiwan MOST 113-2314-B-182A-094-
Corresponding Author	Chien-Hung Chiu, Assistant Professor, MD, Division of Thoracic Surgery, Chang Gung Memorial Hospital, 5 Fu-Shing St. Kwei-Shan, Taoyuan 33305, Taiwan. happy9000000@gmail.com
Key Words	Computed tomography; Cardiopulmonary exercise testing; Hand grip strength; Bioelectrical impedance analysis; Body composition; Morphomics
Core Tip	This study explored the relationship between computed tomography-based morphomics and physical assessments, including bioelectrical impedance analysis, hand grip strength, and cardiopulmonary exercise testing in esophageal cancer patients. Morphomics at the eleventh thoracic vertebra level had the most complete data and showed strong correlations with muscle mass, strength, and exercise capacity. Fat measurements from morphomics were inversely related to exercise performance. Morphomics also demonstrated potential to identify patients with low cardiorespiratory fitness, highlighting its clinical potential as a reliable tool for assessing physical fitness and guiding personalized care in esophageal cancer.
Publish Date	2025-08-25 12:36
Citation	<p>Tseng WHS, Huang SC, Wang SC, Lin J, Zhang P, Liu YC, Chao YK, Chiu CH. Morphomics in esophageal cancer: Validation and association with muscular and cardiorespiratory fitness. <i>World J Gastrointest Surg</i> 2025; 17(8): 108600</p>
URL	https://www.wjgnet.com/1948-9366/full/v17/i8/108600.htm
DOI	https://dx.doi.org/10.4240/wjgs.v17.i8.108600

Full Article (PDF)	WJGS-17-108600-with-cover.pdf
STROBE Statement	108600-STROBE-statement.pdf
Manuscript File	108600_Auto_Edited_073520.docx
Answering Reviewers	108600-answering-reviewers.pdf
Audio Core Tip	108600-audio.mp3
Biostatistics Review Certificate	108600-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	108600-conflict-of-interest-statement.pdf
Copyright License Agreement	108600-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	108600-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	108600-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	108600-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	108600-non-native-speakers.pdf
Supplementary Material	108600-supplementary-material.pdf
Peer-review Report	108600-peer-reviews.pdf
Scientific Editor Work List	108600-scientific-editor-work-list.pdf
CrossCheck Report	108600-crosscheck-report.pdf