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Articles Published Processes
2/10/2026 10:35:33 AM | Browse: 4 | Download: 41
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Received |
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2025-04-21 04:23 |
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Peer-Review Started |
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2025-04-29 09:04 |
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First Decision by Editorial Office Director |
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2025-05-09 12:40 |
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Return for Revision |
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2025-05-09 12:40 |
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Revised |
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2025-05-21 05:34 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-08-20 05:04 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-20 10:58 |
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Articles in Press |
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2025-08-20 10:58 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-29 10:14 |
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Publish the Manuscript Online |
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2026-02-10 10:35 |
| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Opinion Review |
| Article Title |
Decolonizing the gut from multidrug-resistant bacteria: Current strategies and future perspectives
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Anjali Mishra and Deven Juneja |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Deven Juneja, Director, MD, Institute of Critical Care Medicine, Max Super Speciality Hospital, Saket, 1 Press Enclave Road, New Delhi 110017, India. devenjuneja@gmail.com |
| Key Words |
Antimicrobial resistance; Fecal microbiota transplantation; Gut decolonisation; Multidrug-resistant organisms; Selective digestive decontamination |
| Core Tip |
Asymptomatic colonization of the gastrointestinal tract by extended-spectrum β-lactamase or carbapenamase-producing enterobacterales poses a substantial risk of infections caused by these resistant bacteria. Furthermore, this colonization carries a significant risk of transmitting these organisms to other patients and the broader community. Emerging interventions such as faecal microbiota transplantation, phage therapy, engineered probiotics, and Clustered Regularly Interspersed Short Palindromic Repeats—CRISPR-associated protein systems offer new hope for precise and sustainable decolonization. Additionally, dietary interventions and immune modulation may serve as supportive strategies to enhance the resilience of the host microbiota. However, many of these approaches are still in the nascent stage, and their long-term efficacy, safety, and regulatory approval remain barriers to routine clinical application. |
| Publish Date |
2026-02-10 10:35 |
| Citation |
Mishra A, Juneja D. Decolonizing the gut from multidrug-resistant bacteria: Current strategies and future perspectives. World J Methodol 2026; 16(1): 108646 |
| URL |
https://www.wjgnet.com/2222-0682/full/v16/i1/108646.htm |
| DOI |
https://dx.doi.org/10.5662/wjm.v16.i1.108646 |
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