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11/4/2025 2:41:50 AM | Browse: 24 | Download: 53
Publication Name World Journal of Psychiatry
Manuscript ID 108713
Country China
Received
2025-05-23 11:56
Peer-Review Started
2025-05-23 11:56
First Decision by Editorial Office Director
2025-06-17 03:20
Return for Revision
2025-06-17 03:20
Revised
2025-06-29 15:20
Publication Fee Transferred
2025-07-04 07:04
Second Decision by Editor
2025-09-03 09:06
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-09-10 08:31
Articles in Press
2025-09-10 08:31
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-22 02:40
Publish the Manuscript Online
2025-11-04 02:41
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychology
Manuscript Type Review
Article Title From physiology to psychology: An integrative review of menopausal syndrome
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Lin Lang, Chang-Chang Huang, Hong-Yin Cui, Huan-Xin Zhong, Min-Yan Shen and Fen Zhao
ORCID
Author(s) ORCID Number
Fen Zhao http://orcid.org/0009-0009-9256-5140
Funding Agency and Grant Number
Funding Agency Grant Number
Zhejiang Provincial Medical and Health Science and Technology Program 2025KY196
Corresponding Author Fen Zhao, Department of Gynecology, First People’s Hospital of Linping District, No. 369 Yingbin Road, Linping District, Hangzhou 310000, Zhejiang Province, China. zhaofen0508@126.com
Key Words Menopausal syndrome; Depression and anxiety; Estrogen withdrawal; Neuroendocrine and inflammatory mechanisms; Biopsychosocial model
Core Tip This integrative review explores how hormonal fluctuations during menopause contribute to anxiety and depression through neuroendocrine, neuroinflammatory, genetic, psychosocial, and cognitive mechanisms. By bridging physiology and psychology, the paper highlights the complexity of menopausal mental health and advocates for a biopsychosocial framework in clinical care. Understanding these interconnected pathways can inform personalized interventions - ranging from hormone therapy to psychotherapy and lifestyle adjustments - and guide future research on biomarkers and targeted treatments to support emotional wellbeing in midlife women.
Publish Date 2025-11-04 02:41
Citation

Lang XL, Huang CC, Cui HY, Zhong HX, Shen MY, Zhao F. From physiology to psychology: An integrative review of menopausal syndrome. World J Psychiatry 2025; 15(11): 108713

URL https://www.wjgnet.com/2220-3206/full/v15/i11/108713.htm
DOI https://dx.doi.org/10.5498/wjp.v15.i11.108713
Full Article (PDF) WJP-15-108713-with-cover.pdf
Manuscript File 108713_Auto_Edited_014827.docx
Answering Reviewers 108713-answering-reviewers.pdf
Audio Core Tip 108713-audio.mp3
Conflict-of-Interest Disclosure Form 108713-conflict-of-interest-statement.pdf
Copyright License Agreement 108713-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 108713-non-native-speakers.pdf
Peer-review Report 108713-peer-reviews.pdf
Scientific Misconduct Check 108713-scientific-misconduct-check.png
Scientific Editor Work List 108713-scientific-editor-work-list.pdf
CrossCheck Report 108713-crosscheck-report.pdf