Publication Name	World Journal of Diabetes
Manuscript ID	108714
Country	Malaysia

Received	2025-04-22 05:58
Peer-Review Started	2025-04-30 08:58
To Make the First Decision
Return for Revision	2025-06-06 03:12
Revised	2025-07-04 15:23
Second Decision	2025-08-21 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-01 09:35
Articles in Press	2025-09-01 09:35
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-09-21 20:16
Typeset the Manuscript	2025-10-09 02:43
Publish the Manuscript Online	2025-10-15 09:03

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Neurosciences
Manuscript Type	Review
Article Title	Role of astrocytes in diabetic neuropathy: A review of their involvement in disease mechanisms
Manuscript Source	Invited Manuscript
All Author List	Khalilah Haris and Idris Long
ORCID	Author(s) ORCID Number Idris Long http://orcid.org/0000-0002-6828-1908
Funding Agency and Grant Number	Funding Agency Grant Number the Fundamental Research Grant Scheme of the Ministry of Higher Education, Malaysia FRGS/1/2024/SKK10/USM/02/8
Corresponding Author	Idris Long, Associate Professor, Biomedicine programme, School of Health Sciences, Health Campus, Universiti Sains Malaysia, Jalan Hospital USM, Kubang Kerian, Kota Bharu 16150, Kelantan, Malaysia. idriskk@usm.my
Key Words	Glial activation; Astrocytes; Diabetic mellitus; Diabetic neuropathy; Neuroinflammation; Reactive astrogliosis; Oxidative stress; Blood-brain barrier dysfunction; JAK/STAT3 signalling
Core Tip	This paper critically reviews the role of astrocytes in the mechanism of diabetic neuropathy (DN). We discuss the signalling pathways, protein kinases, receptors, and mediators that are involved in the pathophysiology of DN. We also explore the research that focuses on astrocyte activation as a potential treatment for DN.
Publish Date	2025-10-15 09:03
Citation	<p>Haris K, Long I. Role of astrocytes in diabetic neuropathy: A review of their involvement in disease mechanisms. <i>World J Diabetes</i> 2025; 16(10): 108714</p>
URL	https://www.wjgnet.com/1948-9358/full/v16/i10/108714.htm
DOI	https://dx.doi.org/10.4239/wjd.v16.i10.108714

Full Article (PDF)	WJD-16-108714-with-cover.pdf
Manuscript File	108714_Auto_Edited_095053.docx
Answering Reviewers	108714-answering-reviewers.pdf
Audio Core Tip	108714-audio.mp4
Conflict-of-Interest Disclosure Form	108714-conflict-of-interest-statement.pdf
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Non-Native Speakers of English Editing Certificate	108714-non-native-speakers.pdf
Peer-review Report	108714-peer-reviews.pdf
Journal Editor-in-Chief Review Report	108714-journal-editor-in-chief.pdf
Scientific Misconduct Check	108714-scientific-misconduct-check.png
Scientific Editor Work List	108714-scientific-editor-work-list.pdf
CrossCheck Report	108714-crosscheck-report.pdf