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11/19/2025 5:58:04 AM | Browse: 4 | Download: 15
Publication Name World Journal of Transplantation
Manuscript ID 108791
Country Spain
Received
2025-05-12 05:46
Peer-Review Started
2025-05-12 06:09
To Make the First Decision
Return for Revision
2025-06-04 03:02
Revised
2025-06-17 15:43
Second Decision
2025-09-18 02:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-18 09:18
Articles in Press
2025-09-18 09:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-22 03:12
Publish the Manuscript Online
2025-11-19 05:58
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Study
Article Title Chronic kidney disease at one year after liver transplantation: Role of changes in immunosuppression over three decades
Manuscript Source Invited Manuscript
All Author List Alejandro Muñoz-Serrano, María Jesús Citores, Andrea Gutiérrez-Villanueva, Víctor Moreno-Torres, Jorge V López-Ibor, Natalia Vicente and Valentín Cuervas‐Mons
ORCID
Author(s) ORCID Number
Alejandro Muñoz-Serrano http://orcid.org/0000-0002-5152-7799
María Jesús Citores http://orcid.org/0000-0002-6662-2676
Andrea Gutiérrez-Villanueva http://orcid.org/0000-0002-4836-6779
Víctor Moreno-Torres http://orcid.org/0000-0002-9798-4514
Jorge V López-Ibor http://orcid.org/0000-0003-4483-9214
Natalia Vicente http://orcid.org/0000-0001-9620-2667
Valentín Cuervas‐Mons http://orcid.org/0000-0003-3086-9463
Funding Agency and Grant Number
Corresponding Author María Jesús Citores, Laboratory of Internal Medicine, Hospital Universitario Puerta de Hierro Majadahonda, Joaquin Rodrigo 2, Majadahonda 28222, Madrid, Spain. mariajesus.citores@salud.madrid.org
Key Words Chronic kidney disease; Liver transplantation; Tacrolimus; Calcineurin inhibitors; Risk factors
Core Tip This retrospective study evaluated how changes in initial immunosuppression patterns over three decades have affected the evolution of kidney function in the first year after liver transplantation. The risk of chronic kidney disease (CKD) was higher among patients treated with cyclosporine than those treated with tacrolimus (Tac). Addition of basiliximab and mycophenolic acid to the treatment regimen reduced the incidence of CKD in the first year. Elevated Tac blood levels led to acute renal dysfunction at 1 month post-transplant; however, its role in the development of CKD at 1 year post-transplant is less clear, and other non-dose-dependent mechanisms may be involved.
Publish Date 2025-11-19 05:58
Citation <p>Muñoz-Serrano A, Citores MJ, Gutiérrez-Villanueva A, Moreno-Torres V, López-Ibor JV, Vicente N, Cuervas‐Mons V. Chronic kidney disease at one year after liver transplantation: Role of changes in immunosuppression over three decades. <i>World J Transplant</i> 2025; 15(4): 108791</p>
URL https://www.wjgnet.com/2220-3230/full/v15/i4/108791.htm
DOI https://dx.doi.org/10.5500/wjt.v15.i4.108791
Full Article (PDF) WJT-15-108791-with-cover.pdf
Manuscript File 108791_Auto_Edited_090638.docx
Answering Reviewers 108791-answering-reviewers.pdf
Audio Core Tip 108791-audio.mp3
Biostatistics Review Certificate 108791-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 108791-conflict-of-interest-statement.pdf
Copyright License Agreement 108791-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 108791-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 108791-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 108791-non-native-speakers.pdf
Peer-review Report 108791-peer-reviews.pdf
Scientific Misconduct Check 108791-scientific-misconduct-check.png
Scientific Editor Work List 108791-scientific-editor-work-list.pdf
CrossCheck Report 108791-crosscheck-report.pdf