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8/27/2025 9:21:16 AM | Browse: 149 | Download: 225
Publication Name World Journal of Hepatology
Manuscript ID 108845
Country Mexico
Received
2025-04-25 10:57
Peer-Review Started
2025-04-25 10:57
First Decision by Editorial Office Director
2025-05-08 19:26
Return for Revision
2025-05-10 16:50
Revised
2025-05-22 00:56
Publication Fee Transferred
Second Decision by Editor
2025-07-25 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-07-25 08:56
Articles in Press
2025-07-25 08:56
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-14 07:21
Publish the Manuscript Online
2025-08-27 09:21
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Duodenal mucosal ablation by irreversible electroporation: Modulating the gut-liver axis in metabolic steatotic liver disease
Manuscript Source Invited Manuscript
All Author List Mariana M Ramírez-Mejía and Nahum Méndez-Sánchez
ORCID
Author(s) ORCID Number
Mariana M Ramírez-Mejía http://orcid.org/0009-0005-6279-1527
Nahum Méndez-Sánchez http://orcid.org/0000-0001-5257-8048
Funding Agency and Grant Number
Corresponding Author Nahum Méndez-Sánchez, AGAF, FAASLD, FACG, MD, PhD, Liver Research Unit, Medica Sur Clinic and Foundation, Puente de Piedra 150, Col. Toriello Guerra, Mexico City 14050, Mexico. nah@unam.mx
Key Words Gut‒Liver Axis; Metabolic dysfunction-associated steatotic liver disease; Duodenal mucosa ablation; Intestinal permeability; Lipids
Core Tip Duodenal mucosal ablation (DMA) via irreversible electroporation has emerged as a novel strategy to modulate the gut–liver axis in metabolic dysfunction-associated steatotic liver disease (MASLD). In this letter, we analyzed recent preclinical evidence from Yu et al, who reported that DMA leads to reduced hepatic steatosis, improved lipid profiles, and enhanced intestinal barrier integrity. We contextualize these findings within the physiology of the duodenum and explore their translational potential as a minimally invasive therapeutic approach in MASLD.
Publish Date 2025-08-27 09:21
Citation

Ramírez-Mejía MM, Méndez-Sánchez N. Duodenal mucosal ablation by irreversible electroporation: Modulating the gut-liver axis in metabolic steatotic liver disease. World J Hepatol 2025; 17(8): 108845

URL https://www.wjgnet.com/1948-5182/full/v17/i8/108845.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i8.108845
Full Article (PDF) WJH-17-108845-with-cover.pdf
Manuscript File 108845_Auto_Edited_080256.docx
Answering Reviewers 108845-answering-reviewers.pdf
Audio Core Tip 108845-audio.m4a
Conflict-of-Interest Disclosure Form 108845-conflict-of-interest-statement.pdf
Copyright License Agreement 108845-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 108845-non-native-speakers.pdf
Peer-review Report 108845-peer-reviews.pdf
Scientific Misconduct Check 108845-scientific-misconduct-check.png
Scientific Editor Work List 108845-scientific-editor-work-list.pdf
CrossCheck Report 108845-crosscheck-report.pdf