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Articles Published Processes
10/31/2025 3:02:52 PM | Browse: 3 | Download: 2
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Received |
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2025-04-25 10:41 |
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Peer-Review Started |
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2025-04-25 10:41 |
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To Make the First Decision |
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Return for Revision |
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2025-05-14 06:11 |
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Revised |
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2025-05-28 03:26 |
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Second Decision |
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2025-08-07 02:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-08 10:15 |
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Articles in Press |
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2025-08-08 10:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-20 01:51 |
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Publish the Manuscript Online |
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2025-10-31 15:02 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Efficacy and palatability of the developed polyethylene glycol-based formula for the treatment of children with functional constipation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Duc Long Tran and Palittiya Sintusek |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chulalongkorn’s 90-year Scholarship Ratchdapisek Research |
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| Ratchadapiseksompotch Funds, Graduate Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand |
No. GA68/028 |
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| Corresponding Author |
Palittiya Sintusek, MD, PhD, Center of Excellence in Thai Pediatric Gastroenterology, Hepatology and Immunology (TPGHAI), Division of Gastroenterology, Department of Pediatrics, King Chulalongkorn Memorial Hospital, Chulalongkorn University, 254 Phyathai Road, Bangkok 10330, Thailand. palittiya.s@chula.ac.th |
| Key Words |
Constipation; Palatability; Compliance; Polyethylene glycol; Children |
| Core Tip |
Functional constipation (FC), a common functional gastrointestinal disorder in children, affects the quality of life of these children and their families. A combination of osmotic laxatives and toilet training is essential for effective management. Although polyethylene glycol (PEG) is recommended as the first-line treatment, poor palatability often limits patient compliance. This randomized controlled trial compared a newly developed PEG-based formula with the commercialized product, with both formulas being effective and safe. A positive correlation between palatability and compliance was established. Improving taste may be the key to enhancing compliance and improving treatment outcomes in children with FC. |
| Publish Date |
2025-10-31 15:02 |
| Citation |
<p>Tran DL, Sintusek P. Efficacy and palatability of the developed polyethylene glycol-based formula for the treatment of children with functional constipation. <i>World J Clin Pediatr</i> 2025; 14(4): 108854</p> |
| URL |
https://www.wjgnet.com/2219-2808/full/v14/i4/108854.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v14.i4.108854 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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