BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/26/2025 8:19:23 AM | Browse: 268 | Download: 100
Publication Name World Journal of Psychiatry
Manuscript ID 108861
Country China
Received
2025-04-30 08:36
Peer-Review Started
2025-04-30 08:36
To Make the First Decision
Return for Revision
2025-05-22 09:38
Revised
2025-06-04 07:49
Second Decision
2025-08-01 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-08 05:41
Articles in Press
2025-08-08 05:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-15 03:20
Publish the Manuscript Online
2025-09-26 08:19
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Retrospective Study
Article Title Frontal, temporal, cerebellar changes link to sepsis survivors' cognitive issues: A resting state functional magnetic resonance imaging study
Manuscript Source Unsolicited Manuscript
All Author List Ying Li, Jian-Qing Chen, Hui Wang, Jian-Jun Yang and Mu-Huo Ji
ORCID
Author(s) ORCID Number
Jian-Jun Yang http://orcid.org/0000-0002-7694-8813
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82372182, 82172131, and U23A20421
Training Project of the Leading Expert Team: "Jiyang Medical Elites" RC2023-004
Corresponding Author Jian-Jun Yang, PhD, Department of Anesthesiology, Affiliated Zhongda Hospital, School of Medicine, Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing 214400, Jiangsu Province, China. 15852655431@163.com
Key Words Sepsis; Cognitive impairment; Functional magnetic resonance imaging; Graph theory; Granger causality analysis; Topological properties
Core Tip This study innovatively integrates graph theory and Granger causality analysis to uncover distinct topological alterations in frontal, temporal, and cerebellar networks of intensive care unit sepsis survivors. Key findings reveal compensatory hyperconnectivity in the right cerebellum Crus 2, inversely linked to cognitive scores, alongside reduced efficiency in frontal and temporal hubs. Disrupted cerebro-cerebellar directional connectivity further highlights network reorganization post-sepsis. These region-specific network deviations, particularly cerebellar dynamics, offer novel neuroimaging biomarkers for early detection of sepsis-associated cognitive impairment, bridging neuropathological mechanisms with clinical outcomes.
Publish Date 2025-09-26 08:19
Citation <p>Li Y, Chen JQ, Wang H, Yang JJ, Ji MH. Frontal, temporal, cerebellar changes link to sepsis survivors' cognitive issues: A resting state functional magnetic resonance imaging study. <i>World J Psychiatry</i> 2025; 15(10): 108861</p>
URL https://www.wjgnet.com/2220-3206/full/v15/i10/108861.htm
DOI https://dx.doi.org/10.5498/wjp.v15.i10.108861
Full Article (PDF) WJP-15-108861-with-cover.pdf
Manuscript File 108861_Auto_Edited_061006.docx
Answering Reviewers 108861-answering-reviewers.pdf
Audio Core Tip 108861-audio.m4a
Biostatistics Review Certificate 108861-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 108861-conflict-of-interest-statement.pdf
Copyright License Agreement 108861-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 108861-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 108861-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 108861-non-native-speakers.pdf
Supplementary Material 108861-supplementary-material.pdf
Peer-review Report 108861-peer-reviews.pdf
Scientific Misconduct Check 108861-scientific-misconduct-check.png
Scientific Editor Work List 108861-scientific-editor-work-list.pdf
CrossCheck Report 108861-crosscheck-report.pdf