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8/20/2025 8:41:23 AM | Browse: 80 | Download: 136
Publication Name World Journal of Clinical Oncology
Manuscript ID 108865
Country Saudi Arabia
Received
2025-05-06 07:41
Peer-Review Started
2025-05-06 07:42
To Make the First Decision
Return for Revision
2025-05-10 08:18
Revised
2025-05-22 11:03
Second Decision
2025-07-01 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-01 06:18
Articles in Press
2025-07-01 06:18
Publication Fee Transferred
2025-05-25 08:02
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-06 06:53
Publish the Manuscript Online
2025-08-20 08:41
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pathology
Manuscript Type Case Report
Article Title Mutational profile of a Saudi patient with Familial adenomatous polyposis that progressed to colon cancer: A case report
Manuscript Source Unsolicited Manuscript
All Author List Ghada E Esheba, Hala FM Kamel, Heba MK Youssef, Hatoon FM Badawood, Abdullah A Alshamrani, Rehab J Alharbi and Rami Nassir
ORCID
Author(s) ORCID Number
Ghada E Esheba http://orcid.org/0000-0003-1779-3927
Funding Agency and Grant Number
Corresponding Author Ghada E Esheba, Consultant, Full Professor, Department of Histopathology, Security Forces Hospital, Mecca-Al-Taif/Route, Makkah 24251, Saudi Arabia. gesheba@sfhm.med.sa
Key Words Adenomatous polyposis coli gene; Familial adenomatous polyposis; Colorectal cancer; Germline mutation; Adenoma; Next generation sequencing; Case report
Core Tip This case report is the first to highlight the mutation profile of a patient with familial adenomatous polyposis that progressed to colon cancer using next-generation sequencing in Saudi Arabia. The findings provide valuable insight into the genetic landscape of familial adenomatous polyposis-related colorectal cancer in the region. This information may have important prognostic significance and could guide future therapeutic strategies, potentially improving personalized treatment approaches for patients with similar genetic backgrounds.
Publish Date 2025-08-20 08:41
Citation <p>Esheba GE, Kamel HF, Youssef HM, Badawood HF, Alshamrani AA, Alharbi RJ, Nassir R. Mutational profile of a Saudi patient with Familial adenomatous polyposis that progressed to colon cancer: A case report. <i>World J Clin Oncol</i> 2025; 16(8): 108865</p>
URL https://www.wjgnet.com/2218-4333/full/v16/i8/108865.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i8.108865
Full Article (PDF) WJCO-16-108865-with-cover.pdf
CARE Checklist–2016 108865-CARE-Checklist-2016.pdf
Manuscript File 108865_Auto_Edited_013744.docx
Answering Reviewers 108865-answering-reviewers.pdf
Audio Core Tip 108865-audio.m4a
Conflict-of-Interest Disclosure Form 108865-conflict-of-interest-statement.pdf
Copyright License Agreement 108865-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 108865-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 108865-non-native-speakers.pdf
Peer-review Report 108865-peer-reviews.pdf
Scientific Misconduct Check 108865-scientific-misconduct-check.png
Scientific Editor Work List 108865-scientific-editor-work-list.pdf
CrossCheck Report 108865-crosscheck-report.pdf