Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	108870
Country	China

Received	2025-05-14 08:56
Peer-Review Started	2025-05-14 08:56
To Make the First Decision
Return for Revision	2025-06-06 03:05
Revised	2025-06-08 14:02
Second Decision	2025-07-15 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-15 06:46
Articles in Press	2025-07-15 06:46
Publication Fee Transferred	2025-06-13 14:29
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-08-01 06:25
Publish the Manuscript Online	2025-08-14 05:49

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Associations between serum biomarkers and gut microbial imbalance in predicting chemotherapy response in colorectal cancer: A retrospective analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Ming-Zhi Ling, Zhen Wan, Biao Hu, Ming-Jing Zhao, Hao-Sheng Gong and Gang Li
ORCID	Author(s) ORCID Number Gang Li http://orcid.org/0009-0007-0355-1755
Funding Agency and Grant Number
Corresponding Author	Gang Li, Associate Chief Physician, PhD, Department of Laboratory Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, No. 7 Weiwu Road, Zhengzhou 450003, Henan Province, China. ligang65580@126.com
Key Words	Colorectal cancer; S100A12; Soluble CD14; Gut dysbiosis; Fusobacterium nucleatum; Chemotherapy response; Biomarkers; Predictive evaluation
Core Tip	This study highlights the potential of S100A12 and soluble CD14 as non-invasive biomarkers for assessing gut microbial imbalance and predicting chemotherapy responsiveness in colorectal cancer. Their integration into clinical decision-making could support more personalized and effective treatment planning.
Publish Date	2025-08-14 05:49
Citation	<p>Ling MZ, Wan Z, Hu B, Zhao MJ, Gong HS, Li G. Associations between serum biomarkers and gut microbial imbalance in predicting chemotherapy response in colorectal cancer: A retrospective analysis. <i>World J Gastrointest Oncol</i> 2025; 17(8): 108870</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i8/108870.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i8.108870

Full Article (PDF)	WJGO-17-108870-with-cover.pdf
Manuscript File	108870_Auto_Edited_070037.docx
Answering Reviewers	108870-answering-reviewers.pdf
Audio Core Tip	108870-audio.mp3
Biostatistics Review Certificate	108870-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	108870-conflict-of-interest-statement.pdf
Copyright License Agreement	108870-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	108870-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	108870-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	108870-non-native-speakers.pdf
Peer-review Report	108870-peer-reviews.pdf
Scientific Misconduct Check	108870-scientific-misconduct-check.png
Scientific Editor Work List	108870-scientific-editor-work-list.pdf
CrossCheck Report	108870-crosscheck-report.pdf