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11/28/2025 2:00:46 PM | Browse: 36 | Download: 166
Publication Name World Journal of Critical Care Medicine
Manuscript ID 108907
Country Australia
Received
2025-04-27 05:29
Peer-Review Started
2025-04-27 05:29
First Decision by Editorial Office Director
2025-05-20 08:38
Return for Revision
2025-05-20 08:38
Revised
2025-06-02 08:37
Publication Fee Transferred
Second Decision by Editor
2025-08-29 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-08-29 06:59
Articles in Press
2025-08-29 06:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-17 02:01
Publish the Manuscript Online
2025-11-28 14:00
ISSN 2220-3141(online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Retrospective Cohort Study
Article Title Predictive accuracy of 4C Mortality Score and Acute Physiology and Chronic Health Evaluation scores for mortality in COVID-19 patients admitted to intensive care unit
Manuscript Source Invited Manuscript
All Author List Kush Deshpande and Dushyant Tripathi
ORCID
Author(s) ORCID Number
Kush Deshpande http://orcid.org/0000-0003-0482-8158
Dushyant Tripathi http://orcid.org/0000-0002-8162-352X
Funding Agency and Grant Number
Corresponding Author Kush Deshpande, Consultant, MD, Department of Intensive Care, St George Hospital, Gray Street, Kogarah, NSW 2217, Sydney 2217, New South Wales, Australia. kush.deshpande@health.nsw.gov.au
Key Words COVID-19; Mortality; Prediction scores; Acute Physiology and Chronic Health Evaluation II; Acute Physiology and Chronic Health Evaluation III; 4C Mortality Score
Core Tip This retrospective cohort study compared the predictive accuracy of the 4C Mortality Score and Acute Physiology and Chronic Health Evaluation (APACHE) II and III scores for coronavirus disease 2019 patients admitted to intensive care unit (ICU). The 4C score at intensive care unit admission showed an area under the receiver operating characteristic curve of 0.80, higher than at hospital admission (0.75) and comparable to APACHE III (0.79) and II (0.75). Non-survivors were older, predominantly male, with more comorbidities and higher intervention rates. The study suggests that the 4C score at ICU admission is a reliable predictor of mortality and is easier to calculate. These findings warrant further validation in a larger study.
Publish Date 2025-11-28 14:00
Citation

Deshpande K, Tripathi D. Predictive accuracy of 4C Mortality Score and Acute Physiology and Chronic Health Evaluation scores for mortality in COVID-19 patients admitted to intensive care unit. World J Crit Care Med 2025; 14(4): 108907

URL https://www.wjgnet.com/2220-3141/full/v14/i4/108907.htm
DOI https://dx.doi.org/10.5492/wjccm.v14.i4.108907
Full Article (PDF) WJCCM-14-108907-with-cover.pdf
STROBE Statement 108907-STROBE-statement.pdf
Manuscript File 108907_Auto_Edited_010603.docx
Answering Reviewers 108907-answering-reviewers.pdf
Audio Core Tip 108907-audio.mp3
Biostatistics Review Certificate 108907-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 108907-conflict-of-interest-statement.pdf
Copyright License Agreement 108907-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 108907-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 108907-institutional-review-board-statement.pdf
Peer-review Report 108907-peer-reviews.pdf
Scientific Misconduct Check 108907-scientific-misconduct-check.png
Scientific Editor Work List 108907-scientific-editor-work-list.pdf
CrossCheck Report 108907-crosscheck-report.pdf