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1/15/2026 8:12:50 AM | Browse: 1 | Download: 1
Publication Name World Journal of Cardiology
Manuscript ID 108975
Country China
Received
2025-04-30 07:54
Peer-Review Started
2025-04-30 07:54
First Decision by Editorial Office Director
2025-05-17 08:49
Return for Revision
2025-05-17 08:49
Revised
2025-05-30 02:32
Publication Fee Transferred
Second Decision by Editor
2025-12-01 02:52
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-03 09:13
Articles in Press
2025-12-03 09:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-07 03:08
Publish the Manuscript Online
2026-01-15 08:12
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Review
Article Title Clinical application and expansion of paclitaxel-coated balloons in coronary atherosclerotic disease
Manuscript Source Invited Manuscript
All Author List A-Xiu Huang, Hong-Ying Xie, Gang Luo, Le Hong, Yun-Long Zhou, Yun Wang and De-Kui Gao
ORCID
Author(s) ORCID Number
A-Xiu Huang http://orcid.org/0009-0007-1026-4404
Hong-Ying Xie http://orcid.org/0009-0002-1321-7279
Gang Luo http://orcid.org/0009-0005-9981-5625
Le Hong http://orcid.org/0009-0006-8327-5342
Yun-Long Zhou http://orcid.org/0009-0001-1187-3187
Yun Wang http://orcid.org/0000-0002-9490-9690
De-Kui Gao http://orcid.org/0000-0002-0324-9712
Funding Agency and Grant Number
Funding Agency Grant Number
Mianyang Health Commission 2019 Scientific Research Encouragement Project 201948
Corresponding Author De-Kui Gao, Department of Cardiology, Jiangyou Second People's Hospital, No. 31 Juhui Road, Jiangyou 621701, Sichuan Province, China. 635651229@qq.com
Key Words Drug-coated balloon; Coronary artery disease; In-stent restenosis; Bifurcation lesion; Large blood vessel; Small blood vessel; Coronary artery dissection; Complication; Interventional treatment
Core Tip Drug-coated balloon (DCB) angioplasty plays a pivotal role in the interventional management of atherosclerotic cardiovascular disease. This review focuses on the application of paclitaxel DCBs in coronary artery stenosis, encompassing their use in in-stent restenosis, large or small vessel disease, bifurcation lesions, and other lesion types. Key topics include lesion preparation techniques, DCB delivery strategies, complication management, safety evaluations, and post-procedural dual antiplatelet therapy strategies. Additionally, the review explores cellular and molecular mechanisms underlying anti-atherosclerotic and anti-restenotic effects, including endothelial repair, inhibition of neointimal hyperplasia, and modulation of inflammatory pathways. Current challenges and future directions in optimizing DCB-based therapies are also discussed.
Publish Date 2026-01-15 08:12
Citation

Huang AX, Xie HY, Luo G, Hong L, Zhou YL, Wang Y, Gao DK. Clinical application and expansion of paclitaxel-coated balloons in coronary atherosclerotic disease. World J Cardiol 2026; 18(1): 108975

URL https://www.wjgnet.com/1949-8462/full/v18/i1/108975.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i1.108975
Full Article (PDF) WJC-18-108975-with-cover.pdf
Manuscript File 108975_Auto_Edited_090142.docx
Answering Reviewers 108975-answering-reviewers.pdf
Audio Core Tip 108975-audio.mp3
Conflict-of-Interest Disclosure Form 108975-conflict-of-interest-statement.pdf
Copyright License Agreement 108975-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 108975-non-native-speakers.pdf
Peer-review Report 108975-peer-reviews.pdf
Scientific Misconduct Check 108975-scientific-misconduct-check.png
Scientific Editor Work List 108975-scientific-editor-work-list.pdf
CrossCheck Report 108975-crosscheck-report.pdf