Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	109022
Country	India

Received	2025-05-06 06:34
Peer-Review Started	2025-05-06 06:35
To Make the First Decision
Return for Revision	2025-05-17 14:54
Revised	2025-05-31 13:49
Second Decision	2025-09-18 02:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-19 01:30
Articles in Press	2025-09-19 01:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-10-21 10:04
Publish the Manuscript Online	2025-10-31 15:03

ISSN	2219-2808 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Infectious Diseases
Manuscript Type	Randomized Controlled Trial
Article Title	Efficacy of prophylactic intermittent zinc supplementation for reducing acute respiratory infections and diarrhoea in infants:a randomized controlled trial
Manuscript Source	Invited Manuscript
All Author List	Chandra Mohan Kumar, Arnab Ghorui and Karuna Hamsay
ORCID	Author(s) ORCID Number Chandra Mohan Kumar http://orcid.org/0000-0003-1076-6360 Arnab Ghorui http://orcid.org/0009-0007-2213-4885
Funding Agency and Grant Number
Corresponding Author	Arnab Ghorui, Department of Paediatrics, All India Institute of Medical Sciences, Phulwarisharif, Patna 801507, Bihār, India. arnabmck999@gmail.com
Key Words	Prophylactic zinc; Acute respiratory infections; Diarrhoea; Growth; Routine immunization
Core Tip	This randomized controlled trial evaluated the efficacy of prophylactic intermittent zinc supplementation in reducing acute respiratory infections (ARI) and diarrhoea among infants. The study demonstrated that infants receiving zinc supplementation had a significantly lower incidence of ARI and diarrhoea, as well as greater gains in weight and length, compared to the control group. These findings suggest that intermittent zinc supplementation, administered alongside routine vaccinations, is an effective and low-cost strategy to reduce infant morbidity and mortality from ARI and diarrhoea, and can be feasibly implemented in resource-limited healthcare settings.
Publish Date	2025-10-31 15:03
Citation	<p>Kumar CM, Ghorui A, Hamsay K. Efficacy of prophylactic intermittent zinc supplementation for reducing acute respiratory infections and diarrhoea in infants:a randomized controlled trial. <i>World J Clin Pediatr</i> 2025; 14(4): 109022</p>
URL	https://www.wjgnet.com/2219-2808/full/v14/i4/109022.htm
DOI	https://dx.doi.org/10.5409/wjcp.v14.i4.109022

Full Article (PDF)	WJCP-14-109022-with-cover.pdf
CONSORT 2010 Statement	109022-CONSORT-2010-statement.pdf
Manuscript File	109022_Auto_Edited_095520.docx
Answering Reviewers	109022-answering-reviewers.pdf
Audio Core Tip	109022-audio.mp3
Biostatistics Review Certificate	109022-biostatistics-statement.pdf
Clinical Trial Registration Statement	109022-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form	109022-conflict-of-interest-statement.pdf
Copyright License Agreement	109022-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	109022-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	109022-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	109022-non-native-speakers.pdf
Supplementary Material	109022-supplementary-material.pdf
Peer-review Report	109022-peer-reviews.pdf
Scientific Misconduct Check	109022-scientific-misconduct-check.png
Scientific Editor Work List	109022-scientific-editor-work-list.pdf
CrossCheck Report	109022-crosscheck-report.pdf