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Articles Published Processes
9/23/2025 6:48:58 AM | Browse: 39 | Download: 59
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Received |
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2025-04-28 10:17 |
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Peer-Review Started |
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2025-04-28 10:17 |
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To Make the First Decision |
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Return for Revision |
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2025-05-12 10:05 |
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Revised |
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2025-05-26 00:26 |
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Second Decision |
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2025-08-08 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-08 08:15 |
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Articles in Press |
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2025-08-08 08:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-28 08:42 |
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Publish the Manuscript Online |
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2025-09-23 06:48 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Advancing gastric cancer treatment: A comprehensive review of hyperthermic intraperitoneal chemotherapy’s role and outcomes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Fabrizio D'Acapito, Massimo Framarini, Paolo Morgagni, Daniela Di Pietrantonio, Giovanni Vittimberga, Valentina Zucchini and Giorgio Ercolani |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Fabrizio D'Acapito, Consultant, PhD, Department of General and Oncologic Surgery, Morgagni-Pierantoni Hospital, AUSL Romagna, Via Carlo Forlanini 34, Forli 47121, Emilia-Romagna, Italy. fabrizioda@gmail.com |
| Key Words |
Gastric cancer; Peritoneal metastasis; Hyperthermic intraperitoneal chemotherapy; Clinical trial; Outcomes |
| Core Tip |
This systematic review evaluates prospective trials assessing hyperthermic intraperitoneal chemotherapy (HIPEC) in gastric cancer (GC). Therapeutically, HIPEC combined with cytoreductive surgery improves survival in selected patients with peritoneal metastases. Prophylactically, HIPEC reduces peritoneal recurrence after curative gastrectomy in high-risk patients. While promising, outcomes are influenced by heterogeneity in protocols, chemotherapy regimens, and selection criteria. Completeness of cytoreduction remains the strongest predictor of benefit. Future trials should standardize patient selection and HIPEC approaches to clarify its role within multimodal GC treatment strategies. |
| Publish Date |
2025-09-23 06:48 |
| Citation |
<p>D'Acapito F, Framarini M, Morgagni P, Di Pietrantonio D, Vittimberga G, Zucchini V, Ercolani G. Advancing gastric cancer treatment: A comprehensive review of hyperthermic intraperitoneal chemotherapy’s role and outcomes. <i>World J Clin Oncol</i> 2025; 16(9): 109034</p> |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i9/109034.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i9.109034 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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