| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
From gut to liver: Exploring the relationship between inflammatory bowel disease and metabolic dysfunction-associated steatotic liver disease
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Marina Amorim Lopes, Ellen Cristina Souza Oliveira, Ana Elisa Valencise Quaglio, Andrey Santos, Marcello Imbrizi, Leticia Evelyn Rocha Mendes, Rodrigo Fedatto Beraldo, Julio Pinheiro Baima, Amanda Luísa Spiller, Daniéla Oliveira Magro and Ligia Yukie Sassaki |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The São Paulo Research Foundation (FAPESP), Brazil |
No. 2022/15527-3 |
| The Postdoctoral Scholarship Grant from Medical School, São Paulo State University |
No. PROPG/PROPE N° 06/2024 |
| The Master Scholarship Grant from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES)-Programa de Excelência Acadêmica (PROEX) |
No. 88887.807663/2023-00 |
|
| Corresponding Author |
Ligia Yukie Sassaki, Assistant Professor, MD, PhD, Researcher, Department of Internal Medicine, Medical School, São Paulo State University (UNESP), Av. Prof. Montenegro-Distrito de, Botucatu-SP, Botucatu 18618-687, São Paulo, Brazil. ligia.sassaki@unesp.br |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Gut microbiota; Ulcerative colitis; Crohn’s disease; Inflammatory bowel disease |
| Core Tip |
This review explores the complex interplay between inflammatory bowel disease (IBD) and metabolic dysfunction-associated steatotic liver disease, two increasingly prevalent conditions with shared key pathophysiological mechanisms. Chronic inflammation, gut dysbiosis, and intestinal barrier dysfunction are central to both diseases and interconnected through the gut–liver axis. Understanding this relationship highlights the importance of metabolic monitoring, lifestyle interventions, and early screening of hepatic and cardiovascular complications in patients with IBD. |
| Publish Date |
2025-09-25 11:24 |
| Citation |
<p>Lopes MA, Oliveira ECS, Quaglio AEV, Santos A, Imbrizi M, Mendes LER, Beraldo RF, Baima JP, Spiller AL, Magro DO, Sassaki LY. From gut to liver: Exploring the relationship between inflammatory bowel disease and metabolic dysfunction-associated steatotic liver disease. <i>World J Hepatol</i> 2025; 17(9): 109035</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i9/109035.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i9.109035 |
